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TargetPhosphotransferase
LigandBDBM50173779
Substrate/Competitorn/a
Meas. Tech.ChEMBL_330068 (CHEMBL865780)
IC50 3311311214826±n/a nM
Citation Hudock, MPSanz-Rodríguez, CESong, YChan, JMZhang, YOdeh, SKosztowski, TLeon-Rossell, AConcepción, JLYardley, VCroft, SLUrbina, JAOldfield, E Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates. J Med Chem49:215-23 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Phosphotransferase
Name:Phosphotransferase
Synonyms:Hexokinase
Type:PROTEIN
Mol. Mass.:52180.94
Organism:Trypanosoma cruzi
Description:ChEMBL_330068
Residue:471
Sequence:
MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHQMIEGL
EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ
QALQGTAEDLFGFIAQSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDHGFLIKWTKG
FSTRGVEGKDVVELLQKALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN
ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNFQ
TQEKMVSGMYLGEISRRMIAHLAELHCLPSALASKMAKPWSFETKFMGMISADRMPGLQF
TRQVFQELFQVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG
SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50173779
n/a
NameBDBM50173779
Synonyms:2-(1,1'-biphenyl-3-yl)-1-[dihydroxy(oxido)-lambda~4~-sulfanyl]ethylphosphonic acid | 2-biphenyl-3-yl-1-phosphono-ethanesulfonic acid | CHEMBL199653
TypeSmall organic molecule
Emp. Form.C14H15O6PS
Mol. Mass.342.304
SMILESOP(O)(=O)C(Cc1cccc(c1)-c1ccccc1)S(O)(=O)=O
Structure
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