| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine deaminase |
|---|
| Ligand | BDBM22948 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2238229 (CHEMBL5152125) |
|---|
| Ki | 3.6±n/a nM |
|---|
| Citation |  Hou, R; He, Y; Yan, G; Hou, S; Xie, Z; Liao, C Zinc enzymes in medicinal chemistry. Eur J Med Chem226:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine deaminase |
|---|
| Name: | Adenosine deaminase |
|---|
| Synonyms: | ADA_MOUSE | Ada |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39984.63 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_31100 |
|---|
| Residue: | 352 |
|---|
| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYFGKKRGIALPADTVEELRNIIGMDKPLSLPG
FLAKFDYYMPVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPMPWNQT
EGDVTPDDVVDLVNQGLQEGEQAFGIKVRSILCCMRHQPSWSLEVLELCKKYNQKTVVAM
DLAGDETIEGSSLFPGHVEAYEGAVKNGIHRTVHAGEVGSPEVVREAVDILKTERVGHGY
HTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPKTTHAVVRFKNDKANYSLNTDDPLIF
KSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEEEKKELLERLYREYQ
|
|
|
|---|
| BDBM22948 |
|---|
| n/a |
|---|
| Name | BDBM22948 |
|---|
| Synonyms: | 1-[(1R,2S)-2-hydroxy-1-(2-naphthalen-1-ylethyl)propyl]-1H-imidazole-4-carboxamide | 1-[(3R,4S)-4-hydroxy-1-(naphthalen-1-yl)pentan-3-yl]-1H-imidazole-4-carboxamide | CHEMBL93560 | imidazole-4-carboxamide analogue, 5 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H21N3O2 |
|---|
| Mol. Mass. | 323.3889 |
|---|
| SMILES | C[C@H](O)[C@@H](CCc1cccc2ccccc12)n1cnc(c1)C(N)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
