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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bromodomain-containing protein 9 | ||
| Ligand | BDBM50602864 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2242376 (CHEMBL5156586) | ||
| Kd | 2610±n/a nM | ||
| Citation |  Xiang, Q; Wang, C; Wu, T; Zhang, C; Hu, Q; Luo, G; Hu, J; Zhuang, X; Zou, L; Shen, H; Wu, X; Zhang, Y; Kong, X; Liu, J; Xu, Y Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer. J Med Chem65:785-810 (2022) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bromodomain-containing protein 9 | |||
| Name: | Bromodomain-containing protein 9 | ||
| Synonyms: | BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 | Rhabdomyosarcoma antigen MU-RMS-40.8 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 66994.30 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_108000 | ||
| Residue: | 597 | ||
| Sequence: |
| ||
| BDBM50602864 | |||
| n/a | |||
| Name | BDBM50602864 | ||
| Synonyms: | CCS-1477 | CCS1477 | Ccs 1477 | Ccs1477 | INOBRODIB | Inobrodib | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H32F2N4O3 | ||
| Mol. Mass. | 534.5969 | ||
| SMILES | CO[C@H]1CC[C@@H](CC1)n1c(nc2cc(ccc12)-c1c(C)noc1C)[C@@H]1CCCC(=O)N1c1ccc(F)c(F)c1 |r,wU:24.27,5.8,wD:2.1,(-5.83,-7.85,;-6.97,-6.82,;-6.65,-5.31,;-5.19,-4.84,;-4.87,-3.33,;-6.01,-2.3,;-7.48,-2.77,;-7.8,-4.28,;-5.69,-.79,;-4.29,-.17,;-4.45,1.37,;-5.95,1.69,;-6.72,3.02,;-8.26,3.02,;-9.03,1.69,;-8.26,.35,;-6.72,.35,;-9.03,4.35,;-8.41,5.76,;-6.9,6.08,;-9.55,6.79,;-10.89,6.02,;-10.57,4.51,;-11.6,3.37,;-2.95,-.94,;-2.95,-2.48,;-1.62,-3.25,;-.29,-2.48,;-.29,-.94,;1.05,-.17,;-1.62,-.17,;-1.62,1.37,;-.29,2.14,;-.29,3.68,;-1.62,4.45,;-1.62,5.99,;-2.95,3.68,;-4.29,4.45,;-2.95,2.14,)| | ||
| Structure | 
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