| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50605058 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2250263 (CHEMBL5164473) |
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| IC50 | 7.1±n/a nM |
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| Citation |  Kojima, E; Iimuro, A; Nakajima, M; Kinuta, H; Asada, N; Sako, Y; Nakata, Z; Uemura, K; Arita, S; Miki, S; Wakasa-Morimoto, C; Tachibana, Y Pocket-to-Lead: Structure-Based J Med Chem65:6157-6170 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50605058 |
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| n/a |
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| Name | BDBM50605058 |
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| Synonyms: | CHEMBL5208218 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H37NO7S |
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| Mol. Mass. | 519.65 |
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| SMILES | COc1ccc(CN2C[C@H](O)[C@](CCC(C)C)(C2=O)c2ccc(cc2O[C@@H](C)CO)S(C)(=O)=O)cc1 |r| |
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| Structure | 
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