| Reaction Details |
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 | Report a problem with these data |
| Target | Galectin-8 |
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| Ligand | BDBM50605163 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2250679 (CHEMBL5164889) |
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| Kd | 1900000±n/a nM |
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| Citation |  Bum-Erdene, K; Collins, PM; Hugo, MW; Tarighat, SS; Fei, F; Kishor, C; Leffler, H; Nilsson, UJ; Groffen, J; Grice, ID; Heisterkamp, N; Blanchard, H Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J Med Chem65:5975-5989 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Galectin-8 |
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| Name: | Galectin-8 |
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| Synonyms: | Gal-8 | LEG8_HUMAN | LGALS8 | PCTA-1 | Po66 carbohydrate-binding protein | Po66-CBP | Prostate carcinoma tumor antigen 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35814.23 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1454625 |
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| Residue: | 317 |
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| Sequence: | MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRA
DVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNG
KHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGT
PQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFV
RNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSI
DTLEINGDIHLLEVRSW
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| BDBM50605163 |
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| n/a |
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| Name | BDBM50605163 |
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| Synonyms: | CHEMBL5193025 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22F3NO10 |
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| Mol. Mass. | 529.4167 |
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| SMILES | CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](OC(=O)c2ccc(C)cc2)[C@@H]1OC(=O)c1ccc(cc1[N+]([O-])=O)C(F)(F)F |r| |
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| Structure | 
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