| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase RIO2 |
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| Ligand | BDBM50550127 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2253173 (CHEMBL5167383) |
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| Kd | 150±n/a nM |
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| Citation |  Ouyang, Y; Si, H; Zhu, C; Zhong, L; Ma, H; Li, Z; Xiong, H; Liu, T; Liu, Z; Zhang, Z; Zhang, ZM; Cai, Q Discovery of 8-(6-Methoxypyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,5-dihydro- J Med Chem65:7833-7842 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase RIO2 |
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| Name: | Serine/threonine-protein kinase RIO2 |
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| Synonyms: | RIO2 | RIOK2 | RIOK2_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63275.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_655912 |
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| Residue: | 552 |
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| Sequence: | MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPGSLIASIASLKHGGCNKVLRELVKHK
LIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQF
ALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPID
YNRHAVVMELINGYPLCQIHHVEDPASVYDEAMELIVKLANHGLIHGDFNEFNLILDESD
HITMIDFPQMVSTSHPNAEWYFDRDVKCIKDFFMKRFSYESELFPTFKDIRREDTLDVEV
SASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLE
ESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEK
NRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFRDEENVGAMNQYRTR
TLSITSSGSAVSCSTIPPELVKQKVKRQLTKQQKSAVRRRLQKGEANIFTKQRRENMQNI
KSSLEAASFWGE
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| BDBM50550127 |
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| n/a |
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| Name | BDBM50550127 |
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| Synonyms: | CHEMBL4781866 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16N2O |
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| Mol. Mass. | 276.3324 |
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| SMILES | Cc1ccnc(NC(=O)Cc2ccc3ccccc3c2)c1 |
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| Structure | 
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