| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
|---|
| Ligand | BDBM50188256 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_380767 (CHEMBL867360) |
|---|
| EC50 | >10000±n/a nM |
|---|
| Citation |  Epple, R; Russo, R; Azimioara, M; Cow, C; Xie, Y; Wang, X; Wityak, J; Karanewsky, D; Gerken, A; Iskandar, M; Saez, E; Martin Seidel, H; Tian, SS 3,4,5-Trisubstituted isoxazoles as novel PPARdelta agonists: Part 1. Bioorg Med Chem Lett16:4376-80 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peroxisome proliferator-activated receptor gamma |
|---|
| Name: | Peroxisome proliferator-activated receptor gamma |
|---|
| Synonyms: | NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2 |
|---|
| Type: | Nuclear Receptor |
|---|
| Mol. Mass.: | 57613.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P37231 |
|---|
| Residue: | 505 |
|---|
| Sequence: | MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL
LQVIKKTETDMSLHPLLQEIYKDLY
|
|
|
|---|
| BDBM50188256 |
|---|
| n/a |
|---|
| Name | BDBM50188256 |
|---|
| Synonyms: | 2-(3-chloro-4-(4-(4-(2,4-dichlorophenoxy)butanoyl)-5-phenylisoxazol-3-yl)phenyl)acetic acid | CHEMBL215605 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H20Cl3NO5 |
|---|
| Mol. Mass. | 544.81 |
|---|
| SMILES | OC(=O)Cc1ccc(-c2noc(c2C(=O)CCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
