| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50408669 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2267986 |
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| Ki | 2.8±n/a nM |
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| Citation |  Huang, H; Li, X; Xie, P; Li, X; Xu, X; Qian, Y; Yuan, C; Meng, X; Chai, J; Chen, J; Liu, J; Wang, W; Li, W; Wang, Y; Fu, W; Liu, J Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3 J Med Chem64:9458-9483 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44431.62 |
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| Organism: | MOUSE |
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| Description: | OPIATE Mu OPRM1 MOUSE::P42866 |
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| Residue: | 398 |
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| Sequence: | MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50408669 |
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| n/a |
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| Name | BDBM50408669 |
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| Synonyms: | CHEMBL5272171 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27F3N2O4 |
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| Mol. Mass. | 452.4667 |
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| SMILES | CN(C)CC1CN(CCC1(O)c1cccc(O)c1)C(=O)Cc1cccc(OC(F)(F)F)c1 |
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| Structure | 
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