| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50408809 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2267986 |
|---|
| Ki | 82±n/a nM |
|---|
| Citation |  Huang, H; Li, X; Xie, P; Li, X; Xu, X; Qian, Y; Yuan, C; Meng, X; Chai, J; Chen, J; Liu, J; Wang, W; Li, W; Wang, Y; Fu, W; Liu, J Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3 J Med Chem64:9458-9483 (2021) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44431.62 |
|---|
| Organism: | MOUSE |
|---|
| Description: | OPIATE Mu OPRM1 MOUSE::P42866 |
|---|
| Residue: | 398 |
|---|
| Sequence: | MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM50408809 |
|---|
| n/a |
|---|
| Name | BDBM50408809 |
|---|
| Synonyms: | CHEMBL5287093 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H32N2O3 |
|---|
| Mol. Mass. | 432.5546 |
|---|
| SMILES | COc1cccc(c1)C1(O)CCN(CC1CN(C)C)C(=O)Cc1ccc2ccccc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
