| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ubiquitin carboxyl-terminal hydrolase 7 |
|---|
| Ligand | BDBM50250943 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2274027 |
|---|
| IC50 | 17800±n/a nM |
|---|
| Citation |  Li, P; Liu, HM Recent advances in the development of ubiquitin-specific-processing protease 7 (USP7) inhibitors. Eur J Med Chem191:0 (2020) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ubiquitin carboxyl-terminal hydrolase 7 |
|---|
| Name: | Ubiquitin carboxyl-terminal hydrolase 7 |
|---|
| Synonyms: | Deubiquitinating enzyme 7 | HAUSP | Herpesvirus-associated ubiquitin-specific protease | UBP7_HUMAN | USP7 | Ubiquitin thioesterase 7 | Ubiquitin-specific-processing protease 7 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 128274.45 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1469483 |
|---|
| Residue: | 1102 |
|---|
| Sequence: | MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDME
DDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQ
CNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPE
KGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRK
AVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELC
RVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNI
FESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIK
INDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKF
DDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL
VERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS
SLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTI
FLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM
CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSEL
PTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFF
KSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLN
SQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLE
CLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREV
MKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLD
HFNKAPKRSRYTYLEKAIKIHN
|
|
|
|---|
| BDBM50250943 |
|---|
| n/a |
|---|
| Name | BDBM50250943 |
|---|
| Synonyms: | CHEMBL4102930 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H18N2O |
|---|
| Mol. Mass. | 290.359 |
|---|
| SMILES | CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
