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TargetPolyphenol oxidase 2
LigandBDBM50186767
Substrate/Competitorn/a
Meas. Tech.ChEMBL_453186 (CHEMBL902336)
IC50 16520±n/a nM
Citation Song, SLee, HJin, YHa, YMBae, SChung, HYSuh, H Syntheses of hydroxy substituted 2-phenyl-naphthalenes as inhibitors of tyrosinase. Bioorg Med Chem Lett17:461-4 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Polyphenol oxidase 2
Name:Polyphenol oxidase 2
Synonyms:Monophenol monooxygenase | Monophenol oxidase | PPO2 | PPO2_AGABI | Tyrosinase
Type:Protein
Mol. Mass.:63923.66
Organism:Agaricus bisporus (Common mushroom)
Description:O42713
Residue:556
Sequence:
MSLIATVGPTGGVKNRLNIVDFVKNEKFFTLYVRSLELLQAKEQHDYSSFFQLAGIHGLP
FTEWAKERPSMNLYKAGYCTHGQVLFPTWHRTYLSVLEQILQGAAIEVAKKFTSNQTDWV
QAAQDLRQPYWDWGFELMPPDEVIKNEEVNITNYDGKKISVKNPILRYHFHPIDPSFKPY
GDFATWRTTVRNPDRNRREDIPGLIKKMRLEEGQIREKTYNMLKFNDAWERFSNHGISDD
QHANSLESVHDDIHVMVGYGKIEGHMDHPFFAAFDPIFWLHHTNVDRLLSLWKAINPDVW
VTSGRNRDGTMGIAPNAQINSETPLEPFYQSGDKVWTSASLADTARLGYSYPDFDKLVGG
TKELIRDAIDDLIDERYGSKPSSGARNTAFDLLADFKGITKEHKEDLKMYDWTIHVAFKK
FELKESFSLLFYFASDGGDYDQENCFVGSINAFRGTAPETCANCQDNENLIQEGFIHLNH
YLARDLESFEPQDVHKFLKEKGLSYKLYSRGDKPLTSLSVKIEGRPLHLPPGEHRPKYDH
TQARVVFDDVAVHVIN
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  Blast E-value cutoff:
BDBM50186767
n/a
NameBDBM50186767
Synonyms:5-(6-Hydroxy-naphthalen-2-yl)-benzene-1,3-diol | 5-(6-hydroxy-naphtalen-2-yl)-benzene-1,3-diol | 5-(6-hydroxynaphthalen-2-yl)benzene-1,3-diol | CHEMBL197892
TypeSmall organic molecule
Emp. Form.C16H12O3
Mol. Mass.252.2647
SMILESOc1cc(O)cc(c1)-c1ccc2cc(O)ccc2c1
Structure
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