| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 1 |
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| Ligand | BDBM50504348 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2285457 |
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| IC50 | 50±n/a nM |
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| Citation |  Tao, Y; Hao, X; Ding, X; Cherukupalli, S; Song, Y; Liu, X; Zhan, P Medicinal chemistry insights into novel CDC25 inhibitors. Eur J Med Chem201:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 1 |
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| Name: | M-phase inducer phosphatase 1 |
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| Synonyms: | CDC25A | Dual specificity phosphatase (Cdc25A) | Dual specificity phosphatase Cdc25A | M-phase inducer phosphatase 1 | MPIP1_HUMAN | phosphatase Cdc25 |
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| Type: | Protein |
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| Mol. Mass.: | 59090.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30304 |
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| Residue: | 524 |
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| Sequence: | MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE
QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK
RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP
ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL
WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK
ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI
SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT
DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY
CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
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| BDBM50504348 |
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| n/a |
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| Name | BDBM50504348 |
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| Synonyms: | CHEMBL189010 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8O4S |
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| Mol. Mass. | 248.255 |
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| SMILES | OC(=O)CSC1=CC(=O)c2ccccc2C1=O |t:5| |
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| Structure | 
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