| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50216053 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_448359 (CHEMBL898620) |
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| Ki | 102±n/a nM |
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| Citation |  Awadallah, FM; Müller, F; Lehmann, J; Abadi, AH Synthesis of novel lactam derivatives and their evaluation as ligands for the dopamine receptors, leading to a D(4)-selective ligand. Bioorg Med Chem15:5811-8 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50216053 |
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| n/a |
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| Name | BDBM50216053 |
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| Synonyms: | 3-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-quinazolin-4(3H)-one | CHEMBL398813 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25F3N4O |
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| Mol. Mass. | 430.466 |
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| SMILES | FC(F)(F)c1cccc(c1)N1CCN(CCCCn2cnc3ccccc3c2=O)CC1 |
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| Structure | 
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