Compile Data Set for Download or QSAR

Found 243 hits with Last Name = 'awadallah' and Initial = 'fm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216040 (3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)quin...) Show SMILES COc1ccccc1N1CCN(CCCCn2cnc3ccccc3c2=O)CC1 Show InChI InChI=1S/C23H28N4O2/c1-29-22-11-5-4-10-21(22)26-16-14-25(15-17-26)12-6-7-13-27-18-24-20-9-3-2-8-19(20)23(27)28/h2-5,8-11,18H,6-7,12-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216045 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1,2...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C21H25N3O3S/c25-21-19-10-4-5-11-20(19)28(26,27)24(21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50080151 (CHEMBL3040927) Show SMILES NS(=O)(=O)c1ccc(NCc2coc3ccccc3c2=O)cc1 Show InChI InChI=1S/C16H14N2O4S/c17-23(20,21)13-7-5-12(6-8-13)18-9-11-10-22-15-4-2-1-3-14(15)16(11)19/h1-8,10,18H,9H2,(H2,17,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50080145 (CHEMBL3416241) Show SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C\c2coc3ccccc3c2=O)N=C1c1ccccc1 |c:29| Show InChI InChI=1S/C25H17N3O5S/c26-34(31,32)19-12-10-18(11-13-19)28-24(16-6-2-1-3-7-16)27-21(25(28)30)14-17-15-33-22-9-5-4-8-20(22)23(17)29/h1-15H,(H2,26,31,32)/b21-14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50080147 (CHEMBL3416247) Show SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C\c2coc3ccccc3c2=O)N=C1c1ccc(Cl)cc1 |c:29| Show InChI InChI=1S/C25H16ClN3O5S/c26-17-7-5-15(6-8-17)24-28-21(13-16-14-34-22-4-2-1-3-20(22)23(16)30)25(31)29(24)18-9-11-19(12-10-18)35(27,32)33/h1-14H,(H2,27,32,33)/b21-13-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216046 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1,2-benzisothi...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 Show InChI InChI=1S/C22H27N3O4S/c1-29-20-10-4-3-9-19(20)24-16-14-23(15-17-24)12-6-7-13-25-22(26)18-8-2-5-11-21(18)30(25,27)28/h2-5,8-11H,6-7,12-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50080146 (CHEMBL3416242) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(cc2)N2C(=O)\C(=C\c3coc4ccccc4c3=O)N=C2c2ccccc2)no1 |c:33| Show InChI InChI=1S/C29H20N4O6S/c1-18-15-26(31-39-18)32-40(36,37)22-13-11-21(12-14-22)33-28(19-7-3-2-4-8-19)30-24(29(33)35)16-20-17-38-25-10-6-5-9-23(25)27(20)34/h2-17H,1H3,(H,31,32)/b24-16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50080154 (CHEMBL3416235) Show SMILES NS(=O)(=O)c1ccc(NC2=NC(=O)\C(S2)=C/c2coc3ccccc3c2=O)cc1 |t:9| Show InChI InChI=1S/C19H13N3O5S2/c20-29(25,26)13-7-5-12(6-8-13)21-19-22-18(24)16(28-19)9-11-10-27-15-4-2-1-3-14(15)17(11)23/h1-10H,(H2,20,25,26)(H,21,22,24)/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50080152 (CHEMBL3416230) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NCc3coc4ccccc4c3=O)cc2)no1 Show InChI InChI=1S/C20H17N3O5S/c1-13-10-19(22-28-13)23-29(25,26)16-8-6-15(7-9-16)21-11-14-12-27-18-5-3-2-4-17(18)20(14)24/h2-10,12,21H,11H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human cytosolic form of carbonic anhydrase-2 assessed as CO2 hydration activity incubated for 15 mins prior to testing by stopped flow ...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50080154 (CHEMBL3416235) Show SMILES NS(=O)(=O)c1ccc(NC2=NC(=O)\C(S2)=C/c2coc3ccccc3c2=O)cc1 |t:9| Show InChI InChI=1S/C19H13N3O5S2/c20-29(25,26)13-7-5-12(6-8-13)21-19-22-18(24)16(28-19)9-11-10-27-15-4-2-1-3-14(15)17(11)23/h1-10H,(H2,20,25,26)(H,21,22,24)/b16-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human cytosolic form of carbonic anhydrase-2 assessed as CO2 hydration activity incubated for 15 mins prior to testing by stopped flow ...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216044 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H26F3N3O/c24-23(25,26)19-7-5-8-20(16-19)28-14-12-27(13-15-28)10-3-4-11-29-17-18-6-1-2-9-21(18)22(29)30/h1-2,5-9,16H,3-4,10-15,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080154 (CHEMBL3416235) Show SMILES NS(=O)(=O)c1ccc(NC2=NC(=O)\C(S2)=C/c2coc3ccccc3c2=O)cc1 |t:9| Show InChI InChI=1S/C19H13N3O5S2/c20-29(25,26)13-7-5-12(6-8-13)21-19-22-18(24)16(28-19)9-11-10-27-15-4-2-1-3-14(15)17(11)23/h1-10H,(H2,20,25,26)(H,21,22,24)/b16-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080147 (CHEMBL3416247) Show SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C\c2coc3ccccc3c2=O)N=C1c1ccc(Cl)cc1 |c:29| Show InChI InChI=1S/C25H16ClN3O5S/c26-17-7-5-15(6-8-17)24-28-21(13-16-14-34-22-4-2-1-3-20(22)23(16)30)25(31)29(24)18-9-11-19(12-10-18)35(27,32)33/h1-14H,(H2,27,32,33)/b21-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080150 (CHEMBL3416229) Show SMILES CCOC1Oc2ccccc2C(=O)\C1=C\Nc1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C21H19N3O5S2/c1-2-28-20-17(19(25)16-5-3-4-6-18(16)29-20)13-23-14-7-9-15(10-8-14)31(26,27)24-21-22-11-12-30-21/h3-13,20,23H,2H2,1H3,(H,22,24)/b17-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50437929 (CHEMBL2408560) Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1 |w:14.16| Show InChI InChI=1S/C23H21N3O5S/c1-2-30-23-19(22(27)18-7-3-4-8-20(18)31-23)15-25-16-10-12-17(13-11-16)32(28,29)26-21-9-5-6-14-24-21/h3-15,23,25H,2H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080145 (CHEMBL3416241) Show SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C\c2coc3ccccc3c2=O)N=C1c1ccccc1 |c:29| Show InChI InChI=1S/C25H17N3O5S/c26-34(31,32)19-12-10-18(11-13-19)28-24(16-6-2-1-3-7-16)27-21(25(28)30)14-17-15-33-22-9-5-4-8-20(22)23(17)29/h1-15H,(H2,26,31,32)/b21-14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50080150 (CHEMBL3416229) Show SMILES CCOC1Oc2ccccc2C(=O)\C1=C\Nc1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C21H19N3O5S2/c1-2-28-20-17(19(25)16-5-3-4-6-18(16)29-20)13-23-14-7-9-15(10-8-14)31(26,27)24-21-22-11-12-30-21/h3-13,20,23H,2H2,1H3,(H,22,24)/b17-13-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080148 (CHEMBL3416226) Show SMILES CCOC1Oc2ccccc2C(=O)\C1=C\Nc1ccc(cc1)S(=O)(=O)Nc1cc(C)on1 Show InChI InChI=1S/C22H21N3O6S/c1-3-29-22-18(21(26)17-6-4-5-7-19(17)30-22)13-23-15-8-10-16(11-9-15)32(27,28)25-20-12-14(2)31-24-20/h4-13,22-23H,3H2,1-2H3,(H,24,25)/b18-13-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080146 (CHEMBL3416242) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(cc2)N2C(=O)\C(=C\c3coc4ccccc4c3=O)N=C2c2ccccc2)no1 |c:33| Show InChI InChI=1S/C29H20N4O6S/c1-18-15-26(31-39-18)32-40(36,37)22-13-11-21(12-14-22)33-28(19-7-3-2-4-8-19)30-24(29(33)35)16-20-17-38-25-10-6-5-9-23(25)27(20)34/h2-17H,1H3,(H,31,32)/b24-16-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080155 (CHEMBL3416237) Show SMILES O=C1N=C(Nc2ccc(cc2)S(=O)(=O)Nc2ncccn2)S\C1=C\c1coc2ccccc2c1=O |t:2| Show InChI InChI=1S/C23H15N5O5S2/c29-20-14(13-33-18-5-2-1-4-17(18)20)12-19-21(30)27-23(34-19)26-15-6-8-16(9-7-15)35(31,32)28-22-24-10-3-11-25-22/h1-13H,(H,24,25,28)(H,26,27,30)/b19-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216044 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H26F3N3O/c24-23(25,26)19-7-5-8-20(16-19)28-14-12-27(13-15-28)10-3-4-11-29-17-18-6-1-2-9-21(18)22(29)30/h1-2,5-9,16H,3-4,10-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080144 (CHEMBL3416240) Show SMILES O=C1N=C(Nc2ccc(cc2)S(=O)(=O)Nc2ccccn2)S\C1=C\c1coc2ccccc2c1=O |t:2| Show InChI InChI=1S/C24H16N4O5S2/c29-22-15(14-33-19-6-2-1-5-18(19)22)13-20-23(30)27-24(34-20)26-16-8-10-17(11-9-16)35(31,32)28-21-7-3-4-12-25-21/h1-14H,(H,25,28)(H,26,27,30)/b20-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080151 (CHEMBL3040927) Show SMILES NS(=O)(=O)c1ccc(NCc2coc3ccccc3c2=O)cc1 Show InChI InChI=1S/C16H14N2O4S/c17-23(20,21)13-7-5-12(6-8-13)18-9-11-10-22-15-4-2-1-3-14(15)16(11)19/h1-8,10,18H,9H2,(H2,17,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216047 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...) Show SMILES COc1ccccc1N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H29N3O2/c1-28-22-11-5-4-10-21(22)25-16-14-24(15-17-25)12-6-7-13-26-18-19-8-2-3-9-20(19)23(26)27/h2-5,8-11H,6-7,12-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080152 (CHEMBL3416230) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NCc3coc4ccccc4c3=O)cc2)no1 Show InChI InChI=1S/C20H17N3O5S/c1-13-10-19(22-28-13)23-29(25,26)16-8-6-15(7-9-16)21-11-14-12-27-18-5-3-2-4-17(18)20(14)24/h2-10,12,21H,11H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50216052 (2-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)-1-is...) Show SMILES Clc1ccc(cc1)N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C22H26ClN3O/c23-19-7-9-20(10-8-19)25-15-13-24(14-16-25)11-3-4-12-26-17-18-5-1-2-6-21(18)22(26)27/h1-2,5-10H,3-4,11-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human Dopamine D5 receptor expressed in HEK293				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216047 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...) Show SMILES COc1ccccc1N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H29N3O2/c1-28-22-11-5-4-10-21(22)25-16-14-24(15-17-25)12-6-7-13-26-18-19-8-2-3-9-20(19)23(26)27/h2-5,8-11H,6-7,12-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216048 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-i...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)Cc2ccccc12 Show InChI InChI=1S/C22H27N3O/c26-22-21-11-5-4-8-19(21)18-25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50080149 (CHEMBL3416228) Show SMILES CCOC1Oc2ccccc2C(=O)\C1=C\Nc1ccc(cc1)S(=O)(=O)Nc1nc(C)cc(C)n1 Show InChI InChI=1S/C24H24N4O5S/c1-4-32-23-20(22(29)19-7-5-6-8-21(19)33-23)14-25-17-9-11-18(12-10-17)34(30,31)28-24-26-15(2)13-16(3)27-24/h5-14,23,25H,4H2,1-3H3,(H,26,27,28)/b20-14-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216045 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1,2...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C21H25N3O3S/c25-21-19-10-4-5-11-20(19)28(26,27)24(21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216041 (3-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)quin...) Show SMILES O=c1n(CCCCN2CCN(CC2)c2ccccc2)cnc2ccccc12 Show InChI InChI=1S/C22H26N4O/c27-22-20-10-4-5-11-21(20)23-18-26(22)13-7-6-12-24-14-16-25(17-15-24)19-8-2-1-3-9-19/h1-5,8-11,18H,6-7,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216048 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-i...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)Cc2ccccc12 Show InChI InChI=1S/C22H27N3O/c26-22-21-11-5-4-8-19(21)18-25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50437929 (CHEMBL2408560) Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1 |w:14.16| Show InChI InChI=1S/C23H21N3O5S/c1-2-30-23-19(22(27)18-7-3-4-8-20(18)31-23)15-25-16-10-12-17(13-11-16)32(28,29)26-21-9-5-6-14-24-21/h3-15,23,25H,2H2,1H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216045 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1,2...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C21H25N3O3S/c25-21-19-10-4-5-11-20(19)28(26,27)24(21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216053 (3-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCn2cnc3ccccc3c2=O)CC1 Show InChI InChI=1S/C23H25F3N4O/c24-23(25,26)18-6-5-7-19(16-18)29-14-12-28(13-15-29)10-3-4-11-30-17-27-21-9-2-1-8-20(21)22(30)31/h1-2,5-9,16-17H,3-4,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50080145 (CHEMBL3416241) Show SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C\c2coc3ccccc3c2=O)N=C1c1ccccc1 |c:29| Show InChI InChI=1S/C25H17N3O5S/c26-34(31,32)19-12-10-18(11-13-19)28-24(16-6-2-1-3-7-16)27-21(25(28)30)14-17-15-33-22-9-5-4-8-20(22)23(17)29/h1-15H,(H2,26,31,32)/b21-14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human cytosolic form of carbonic anhydrase-2 assessed as CO2 hydration activity incubated for 15 mins prior to testing by stopped flow ...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50216047 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...) Show SMILES COc1ccccc1N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H29N3O2/c1-28-22-11-5-4-10-21(22)25-16-14-24(15-17-25)12-6-7-13-26-18-19-8-2-3-9-20(19)23(26)27/h2-5,8-11H,6-7,12-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human Dopamine D5 receptor expressed in HEK293				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50080149 (CHEMBL3416228) Show SMILES CCOC1Oc2ccccc2C(=O)\C1=C\Nc1ccc(cc1)S(=O)(=O)Nc1nc(C)cc(C)n1 Show InChI InChI=1S/C24H24N4O5S/c1-4-32-23-20(22(29)19-7-5-6-8-21(19)33-23)14-25-17-9-11-18(12-10-17)34(30,31)28-24-26-15(2)13-16(3)27-24/h5-14,23,25H,4H2,1-3H3,(H,26,27,28)/b20-14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50216048 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-i...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)Cc2ccccc12 Show InChI InChI=1S/C22H27N3O/c26-22-21-11-5-4-8-19(21)18-25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human Dopamine D5 receptor expressed in HEK293				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216039 (1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-ind...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H27N3O/c26-22-18-19-8-4-5-11-21(19)25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50216044 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H26F3N3O/c24-23(25,26)19-7-5-8-20(16-19)28-14-12-27(13-15-28)10-3-4-11-29-17-18-6-1-2-9-21(18)22(29)30/h1-2,5-9,16H,3-4,10-15,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human Dopamine D5 receptor expressed in HEK293				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50080155 (CHEMBL3416237) Show SMILES O=C1N=C(Nc2ccc(cc2)S(=O)(=O)Nc2ncccn2)S\C1=C\c1coc2ccccc2c1=O |t:2| Show InChI InChI=1S/C23H15N5O5S2/c29-20-14(13-33-18-5-2-1-4-17(18)20)12-19-21(30)27-23(34-19)26-15-6-8-16(9-7-15)35(31,32)28-22-24-10-3-11-25-22/h1-13H,(H,24,25,28)(H,26,27,30)/b19-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...				Eur J Med Chem 96: 425-35 (2015) Article DOI: 10.1016/j.ejmech.2015.04.033 BindingDB Entry DOI: 10.7270/Q2T155BV
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216053 (3-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCn2cnc3ccccc3c2=O)CC1 Show InChI InChI=1S/C23H25F3N4O/c24-23(25,26)18-6-5-7-19(16-18)29-14-12-28(13-15-29)10-3-4-11-30-17-27-21-9-2-1-8-20(21)22(30)31/h1-2,5-9,16-17H,3-4,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 Show InChI InChI=1S/C22H24F3N3O3S/c23-22(24,25)17-6-5-7-18(16-17)27-14-12-26(13-15-27)10-3-4-11-28-21(29)19-8-1-2-9-20(19)32(28,30)31/h1-2,5-9,16H,3-4,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 Show InChI InChI=1S/C22H24F3N3O3S/c23-22(24,25)17-6-5-7-18(16-17)27-14-12-26(13-15-27)10-3-4-11-28-21(29)19-8-1-2-9-20(19)32(28,30)31/h1-2,5-9,16H,3-4,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50216047 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...) Show SMILES COc1ccccc1N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H29N3O2/c1-28-22-11-5-4-10-21(22)25-16-14-24(15-17-25)12-6-7-13-26-18-19-8-2-3-9-20(19)23(26)27/h2-5,8-11H,6-7,12-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	137	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine D5 receptor in HEK293 cells assessed as change in SKF 38393-induced intracellular calcium response				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216050 (3-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)quina...) Show SMILES Clc1ccc(cc1)N1CCN(CCCCn2cnc3ccccc3c2=O)CC1 Show InChI InChI=1S/C22H25ClN4O/c23-18-7-9-19(10-8-18)26-15-13-25(14-16-26)11-3-4-12-27-17-24-21-6-2-1-5-20(21)22(27)28/h1-2,5-10,17H,3-4,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair

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