| Reaction Details |
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 | Report a problem with these data |
| Target | Protein ADM2 |
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| Ligand | BDBM50025076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_556927 (CHEMBL954953) |
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| IC50 | 2003±n/a nM |
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| Citation |  Miranda, LP; Holder, JR; Shi, L; Bennett, B; Aral, J; Gegg, CV; Wright, M; Walker, K; Doellgast, G; Rogers, R; Li, H; Valladares, V; Salyers, K; Johnson, E; Wild, K Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor. J Med Chem51:7889-97 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein ADM2 |
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| Name: | Protein ADM2 |
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| Synonyms: | ADM2 | ADM2_HUMAN | AM2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 15883.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_556927 |
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| Residue: | 148 |
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| Sequence: | MARIPTAALGCISLLCLQLPGSLSRSLGGDPRPVKPREPPARSPSSSLQPRHPAPRPVVW
KLHRALQAQRGAGLAPVMGQPLRDGGRQHSGPRRHSGPRRTQAQLLRVGCVLGTCQVQNL
SHRLWQLMGPAGRQDSAPVDPSSPHSYG
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| BDBM50025076 |
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| n/a |
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| Name | BDBM50025076 |
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| Synonyms: | CHEMBL2372194 |
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| Type | Small organic molecule |
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| Emp. Form. | C176H262N44O41 |
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| Mol. Mass. | 3650.2337 |
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| SMILES | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](C(C)C)C(=O)N1C2CCCCC2CC1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N1C2CCCCC2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O |r| |
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| Structure | 
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