| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 4,4'-diapophytoene synthase |
|---|
| Ligand | BDBM50268510 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_523732 (CHEMBL1007539) |
|---|
| Ki | 40±n/a nM |
|---|
| Citation |  Song, Y; Liu, CI; Lin, FY; No, JH; Hensler, M; Liu, YL; Jeng, WY; Low, J; Liu, GY; Nizet, V; Wang, AH; Oldfield, E Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. J Med Chem52:3869-80 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 4,4'-diapophytoene synthase |
|---|
| Name: | 4,4'-diapophytoene synthase |
|---|
| Synonyms: | CRTM_STAAU | Dehydrosqualene synthase | crtM |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 34309.10 |
|---|
| Organism: | Staphylococcus aureus |
|---|
| Description: | ChEMBL_1352846 |
|---|
| Residue: | 287 |
|---|
| Sequence: | MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFL
NQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMF
ETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENE
RIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPI
IELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKYHRI
|
|
|
|---|
| BDBM50268510 |
|---|
| n/a |
|---|
| Name | BDBM50268510 |
|---|
| Synonyms: | CHEMBL495624 | N-[3-(3-Phenoxyphenyl)propyl]phosphonoacetamide DipotassiumSalt | dipotassium (2-oxo-2-{[3-(3-phenoxyphenyl)propyl]amino}ethyl)phosphonate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H18NO5P |
|---|
| Mol. Mass. | 347.3034 |
|---|
| SMILES | [O-]P([O-])(=O)CC(=O)NCCCc1cccc(Oc2ccccc2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
