| Reaction Details |
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 | Report a problem with these data |
| Target | 4,4'-diapophytoene synthase |
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| Ligand | BDBM50268679 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_523732 (CHEMBL1007539) |
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| Ki | >7000±n/a nM |
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| Citation |  Song, Y; Liu, CI; Lin, FY; No, JH; Hensler, M; Liu, YL; Jeng, WY; Low, J; Liu, GY; Nizet, V; Wang, AH; Oldfield, E Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. J Med Chem52:3869-80 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 4,4'-diapophytoene synthase |
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| Name: | 4,4'-diapophytoene synthase |
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| Synonyms: | CRTM_STAAU | Dehydrosqualene synthase | crtM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34309.10 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_1352846 |
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| Residue: | 287 |
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| Sequence: | MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFL
NQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMF
ETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENE
RIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPI
IELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKYHRI
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| BDBM50268679 |
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| n/a |
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| Name | BDBM50268679 |
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| Synonyms: | CHEMBL523897 | N-[3-(3-Phenoxyphenyl)propyl]phosphonomalonamide Potassium Salt |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18NO4 |
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| Mol. Mass. | 312.3404 |
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| SMILES | [O-]C(=O)CC(=O)NCCCc1cccc(Oc2ccccc2)c1 |
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| Structure | 
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