Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50285890 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_79817 (CHEMBL695236) |
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IC50 | 3.3±n/a nM |
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Citation | Kempf, DJ; Flentge, CA; Wideburg, NE; Saldivar, A; Vasavanonda, S; Norbeck, DW Evaluation of substituted benzamides as P2 ligands for symmetry-based inhibitors of HIV protease Bioorg Med Chem Lett5:2725-2728 (1995) Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50285890 |
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n/a |
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Name | BDBM50285890 |
Synonyms: | CHEMBL93566 | [(1S,3S,4S)-4-(5-Amino-2-chloro-benzoylamino)-1-benzyl-3-hydroxy-5-phenyl-pentyl]-carbamic acid tert-butyl ester |
Type | Small organic molecule |
Emp. Form. | C30H36ClN3O4 |
Mol. Mass. | 538.078 |
SMILES | CC(C)(C)OC(=O)N[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(N)ccc1Cl)Cc1ccccc1 |
Structure |
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