| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50285894 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_79817 (CHEMBL695236) |
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| IC50 | 23±n/a nM |
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| Citation |  Kempf, DJ; Flentge, CA; Wideburg, NE; Saldivar, A; Vasavanonda, S; Norbeck, DW Evaluation of substituted benzamides as P2 ligands for symmetry-based inhibitors of HIV protease Bioorg Med Chem Lett5:2725-2728 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50285894 |
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| n/a |
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| Name | BDBM50285894 |
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| Synonyms: | CHEMBL541982 | [(1S,3S,4S)-1-Benzyl-3-hydroxy-4-(3-methoxy-benzoylamino)-5-phenyl-pentyl]-carbamic acid tert-butyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C31H38N2O5 |
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| Mol. Mass. | 518.6438 |
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| SMILES | COc1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C |
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| Structure | 
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