| Reaction Details |
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 | Report a problem with these data |
| Target | Isocitrate lyase |
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| Ligand | BDBM50329698 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_675509 (CHEMBL1273722) |
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| IC50 | 21210±n/a nM |
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| Citation |  Oh, KB; Jeon, HB; Han, YR; Lee, YJ; Park, J; Lee, SH; Yang, D; Kwon, M; Shin, J; Lee, HS Bromophenols as Candida albicans isocitrate lyase inhibitors. Bioorg Med Chem Lett20:6644-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Isocitrate lyase |
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| Name: | Isocitrate lyase |
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| Synonyms: | ACEA_CANAX | ICL1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61398.95 |
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| Organism: | Candida albicans |
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| Description: | ChEMBL_972063 |
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| Residue: | 550 |
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| Sequence: | MPYTPIDIQKEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQA
DKLFKLLETHDADKTVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLA
DYPMDTVPNKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGI
TAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGS
NLLAVARTDSEAATLITSTIDHRDHYFIIGATNPEAGDLAALMAEAESKGIYGNELAAIE
SEWTKKAGLKLFHEAVIDEIKNGNYSNKDALIKKFTDKVNPLSHTSHKEAKKLAKELTGK
DIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYAQAKEFADGVKA
AVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGKLGYVWQFITLAGLHTTALAVDDFSN
QYSQIGMKAYGQTVQQPEIEKGVEVVKHQKWSGATYIDGLLKMVSGGVTSTAAMGQGVTE
DQFKESKAKA
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| BDBM50329698 |
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| n/a |
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| Name | BDBM50329698 |
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| Synonyms: | 2,2'-Dibromo-4,4',5,5'-tetrahydroxybibenzyl | CHEMBL1269460 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12Br2O4 |
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| Mol. Mass. | 404.051 |
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| SMILES | Oc1cc(Br)c(CCc2cc(O)c(O)cc2Br)cc1O |
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| Structure | 
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