| Reaction Details |
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 | Report a problem with these data |
| Target | Isocitrate lyase |
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| Ligand | BDBM50206193 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_687440 (CHEMBL1292116) |
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| IC50 | 75000±n/a nM |
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| Citation |  Lee, YJ; Han, YR; Park, W; Nam, SH; Oh, KB; Lee, HS Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. Bioorg Med Chem Lett20:6882-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Isocitrate lyase |
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| Name: | Isocitrate lyase |
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| Synonyms: | ACEA_CANAX | ICL1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61398.95 |
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| Organism: | Candida albicans |
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| Description: | ChEMBL_972063 |
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| Residue: | 550 |
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| Sequence: | MPYTPIDIQKEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQA
DKLFKLLETHDADKTVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLA
DYPMDTVPNKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGI
TAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGS
NLLAVARTDSEAATLITSTIDHRDHYFIIGATNPEAGDLAALMAEAESKGIYGNELAAIE
SEWTKKAGLKLFHEAVIDEIKNGNYSNKDALIKKFTDKVNPLSHTSHKEAKKLAKELTGK
DIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYAQAKEFADGVKA
AVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGKLGYVWQFITLAGLHTTALAVDDFSN
QYSQIGMKAYGQTVQQPEIEKGVEVVKHQKWSGATYIDGLLKMVSGGVTSTAAMGQGVTE
DQFKESKAKA
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| BDBM50206193 |
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| n/a |
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| Name | BDBM50206193 |
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| Synonyms: | 1-(3-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole | CHEMBL241098 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18N2O |
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| Mol. Mass. | 278.3483 |
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| SMILES | COc1cccc(c1)C1NCCc2c1[nH]c1ccccc21 |w:8.8| |
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| Structure | 
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