| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
|---|
| Ligand | BDBM50134488 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_106190 |
|---|
| EC50 | 24±n/a nM |
|---|
| Citation |  Dyck, B; Parker, J; Phillips, T; Carter, L; Murphy, B; Summers, R; Hermann, J; Baker, T; Cismowski, M; Saunders, J; Goodfellow, V Aryl piperazine melanocortin MC4 receptor agonists. Bioorg Med Chem Lett13:3793-6 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocortin receptor 4 |
|---|
| Name: | Melanocortin receptor 4 |
|---|
| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 36949.50 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P32245 |
|---|
| Residue: | 332 |
|---|
| Sequence: | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
|
|
|
|---|
| BDBM50134488 |
|---|
| n/a |
|---|
| Name | BDBM50134488 |
|---|
| Synonyms: | (R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-4-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide | CHEMBL333283 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H34ClN7O2 |
|---|
| Mol. Mass. | 584.111 |
|---|
| SMILES | Clc1ccc(C[C@@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCN(CC2)c2ccccc2Cn2cnnc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
