Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558038 (CHEMBL4798311) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558038 (CHEMBL4798311) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558042 (CHEMBL4760798) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558042 (CHEMBL4760798) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558040 (CHEMBL4791094) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558040 (CHEMBL4791094) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558043 (CHEMBL4742346) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558043 (CHEMBL4742346) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558044 (CHEMBL4796474) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558044 (CHEMBL4796474) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50547989 (CHEMBL4747872) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50547989 (CHEMBL4747872) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558039 (CHEMBL4752265) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558039 (CHEMBL4752265) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558041 (CHEMBL4783899) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 145 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558041 (CHEMBL4783899) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 145 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558037 (CHEMBL4794137) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 912 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Relaxin-3 receptor 2 (Homo sapiens (Human)) | BDBM50558037 (CHEMBL4794137) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 912 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01786 BindingDB Entry DOI: 10.7270/Q2PC3624 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50399931 (CHEMBL2181207) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of human ERG expressed in rat after 2 to 3 days by patch clamp assay | J Med Chem 55: 10387-404 (2012) Article DOI: 10.1021/jm300831b BindingDB Entry DOI: 10.7270/Q2N017PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50396334 (CHEMBL2170034) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocyte assessed as inhibition of [3H]chloroquine uptake... | J Med Chem 55: 6948-67 (2012) Article DOI: 10.1021/jm300802s BindingDB Entry DOI: 10.7270/Q2319X1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50396333 (CHEMBL2170036) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocyte assessed as inhibition of [3H]chloroquine uptake... | J Med Chem 55: 6948-67 (2012) Article DOI: 10.1021/jm300802s BindingDB Entry DOI: 10.7270/Q2319X1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50563441 (CHEMBL4745810) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocyte assessed as inhibition of [3H]-CQ transport incubated for 1.5 hrs by m... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113227 BindingDB Entry DOI: 10.7270/Q2R49VH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM519 ((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes assessed as reduction in [3H]-chloroquine uptak... | J Med Chem 55: 10387-404 (2012) Article DOI: 10.1021/jm300831b BindingDB Entry DOI: 10.7270/Q2N017PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM519 ((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocyte assessed as inhibition of [3H]chloroquine uptake... | J Med Chem 55: 6948-67 (2012) Article DOI: 10.1021/jm300802s BindingDB Entry DOI: 10.7270/Q2319X1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50563442 (CHEMBL4754685) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocyte assessed as inhibition of [3H]-CQ transport incubated for 1.5 hrs by m... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113227 BindingDB Entry DOI: 10.7270/Q2R49VH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50338982 ((R)-5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocyte assessed as inhibition of [3H]chloroquine uptake... | J Med Chem 55: 6948-67 (2012) Article DOI: 10.1021/jm300802s BindingDB Entry DOI: 10.7270/Q2319X1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50338982 ((R)-5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes assessed as reduction in [3H]-chloroquine uptak... | J Med Chem 55: 10387-404 (2012) Article DOI: 10.1021/jm300831b BindingDB Entry DOI: 10.7270/Q2N017PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM81939 (CAS_52-53-9 | NSC_62969 | VERAPAMIL) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes plasma membrane assessed as reduction of [3H]-c... | ACS Med Chem Lett 5: 576-81 (2014) Article DOI: 10.1021/ml5000228 BindingDB Entry DOI: 10.7270/Q22V2HPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50353744 (CHEMBL1830986) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cape Town Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 chloroquine resistance transporter expressed in xenopus laevis oocytes assessed as inhi... | J Med Chem 54: 6956-68 (2011) Article DOI: 10.1021/jm2009698 BindingDB Entry DOI: 10.7270/Q2GB24FN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM35938 (1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes plasma membrane assessed as reduction of [3H]-c... | ACS Med Chem Lett 5: 576-81 (2014) Article DOI: 10.1021/ml5000228 BindingDB Entry DOI: 10.7270/Q22V2HPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50563440 (CHEMBL4784051) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocyte assessed as inhibition of [3H]-CQ transport incubated for 1.5 hrs by m... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113227 BindingDB Entry DOI: 10.7270/Q2R49VH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50353743 (CHEMBL1830985) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cape Town Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 chloroquine resistance transporter expressed in xenopus laevis oocytes assessed as inhi... | J Med Chem 54: 6956-68 (2011) Article DOI: 10.1021/jm2009698 BindingDB Entry DOI: 10.7270/Q2GB24FN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50020157 (CHEMBL3288457) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes plasma membrane assessed as reduction of [3H]-c... | ACS Med Chem Lett 5: 576-81 (2014) Article DOI: 10.1021/ml5000228 BindingDB Entry DOI: 10.7270/Q22V2HPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50563439 (CHEMBL4748649) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocyte assessed as inhibition of [3H]-CQ transport incubated for 1.5 hrs by m... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113227 BindingDB Entry DOI: 10.7270/Q2R49VH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50020159 (CHEMBL3286418) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes plasma membrane assessed as reduction of [3H]-c... | ACS Med Chem Lett 5: 576-81 (2014) Article DOI: 10.1021/ml5000228 BindingDB Entry DOI: 10.7270/Q22V2HPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM71542 ((4-amino-1-methyl-butyl)-(6-methoxy-8-quinolyl)ami...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes plasma membrane assessed as reduction of [3H]-c... | ACS Med Chem Lett 5: 576-81 (2014) Article DOI: 10.1021/ml5000228 BindingDB Entry DOI: 10.7270/Q22V2HPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50353745 (CHEMBL1830987) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cape Town Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 chloroquine resistance transporter expressed in xenopus laevis oocytes assessed as inhi... | J Med Chem 54: 6956-68 (2011) Article DOI: 10.1021/jm2009698 BindingDB Entry DOI: 10.7270/Q2GB24FN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50017696 ((2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiaz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes plasma membrane assessed as reduction of [3H]-c... | ACS Med Chem Lett 5: 576-81 (2014) Article DOI: 10.1021/ml5000228 BindingDB Entry DOI: 10.7270/Q22V2HPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50020160 (CHEMBL3288467) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes plasma membrane assessed as reduction of [3H]-c... | ACS Med Chem Lett 5: 576-81 (2014) Article DOI: 10.1021/ml5000228 BindingDB Entry DOI: 10.7270/Q22V2HPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50399930 (CHEMBL2181208) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.28E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes assessed as reduction in [3H]-chloroquine uptak... | J Med Chem 55: 10387-404 (2012) Article DOI: 10.1021/jm300831b BindingDB Entry DOI: 10.7270/Q2N017PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chloroquine resistance transporter (Plasmodium falciparum) | BDBM50020154 (CHEMBL3288452) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Australian National University Curated by ChEMBL | Assay Description Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes plasma membrane assessed as reduction of [3H]-c... | ACS Med Chem Lett 5: 576-81 (2014) Article DOI: 10.1021/ml5000228 BindingDB Entry DOI: 10.7270/Q22V2HPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 3 (Homo sapiens (Human)) | BDBM50029747 ((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 3 receptor (hMC3R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 3 (Homo sapiens (Human)) | BDBM50119368 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 3 receptor (hMC3R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 3 (Homo sapiens (Human)) | BDBM50134488 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 3 receptor (hMC3R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 3 (Homo sapiens (Human)) | BDBM50134486 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 3 receptor (hMC3R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenocorticotropic hormone receptor (Mus musculus) | BDBM50134486 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50134487 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 470 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description Agonistic activity measured as inhibition of cAMP accumulation in HEK cells expressing human Melanocortin 4 receptor (hMC4R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Mus musculus) | BDBM50134488 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 4 receptor (mMC4R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenocorticotropic hormone receptor (Mus musculus) | BDBM50119368 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50134489 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description Agonistic activity measured as inhibition of cAMP accumulation in HEK cells expressing human Melanocortin 4 receptor (hMC4R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair |
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