| Reaction Details |
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 | Report a problem with these data |
| Target | Pyruvate kinase PKM |
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| Ligand | BDBM50367051 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_160255 (CHEMBL767869) |
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| Ki | 500000±n/a nM |
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| Citation |  Hai, TT; Abo, M; Hampton, A Species- or isozyme-specific enzyme inhibitors. 9. Selective effects in inhibitions of rat pyruvate kinase isozymes by adenosine 5'-diphosphate derivatives. J Med Chem25:1184-8 (1983) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Pyruvate kinase PKM |
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| Name: | Pyruvate kinase PKM |
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| Synonyms: | KPYM_RAT | Pkm | Pkm2 | Pykm | Pyruvate kinase isozymes M1/M2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57820.70 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_160255 |
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| Residue: | 531 |
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| Sequence: | MPKPDSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEM
LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIR
TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
ISLQVKEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
FASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
LSGETAKGDYPLEAVRMQHLIAREAEAAVFHRLLFEELARASSQSTDPLEAMAMGSVEAS
YKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLD
AWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
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|
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| BDBM50367051 |
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| n/a |
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| Name | BDBM50367051 |
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| Synonyms: | CHEMBL606059 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H20N6O10P2 |
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| Mol. Mass. | 470.2689 |
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| SMILES | CCNc1nc2c(N)ncnc2n1C1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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