| Reaction Details |
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 | Report a problem with these data |
| Target | Leukotriene B4 receptor 1 |
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| Ligand | BDBM50037044 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_99667 (CHEMBL705075) |
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| IC50 | 30±n/a nM |
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| Citation |  Hibi, S; Okamoto, Y; Tagami, K; Numata, H; Kobayashi, N; Shinoda, M; Kawahara, T; Murakami, M; Oketani, K; Inoue, T Novel dual inhibitors of 5-lipoxygenase and thromboxane A2 synthetase: synthesis and structure-activity relationships of 3-pyridylmethyl-substituted 2-amino-6-hydroxybenzothiazole derivatives. J Med Chem37:3062-70 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Leukotriene B4 receptor 1 |
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| Name: | Leukotriene B4 receptor 1 |
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| Synonyms: | BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37582.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15722 |
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| Residue: | 352 |
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| Sequence: | MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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| BDBM50037044 |
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| n/a |
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| Name | BDBM50037044 |
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| Synonyms: | 4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylamino)-methyl]-benzenesulfonamide | CHEMBL318809 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19N3O3S2 |
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| Mol. Mass. | 377.481 |
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| SMILES | Cc1c(C)c2nc(NCc3ccc(cc3)S(N)(=O)=O)sc2c(C)c1O |
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| Structure | 
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