Compile Data Set for Download or QSAR

Found 52 hits with Last Name = 'numata' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037039 (2-Amino-5,7-dimethyl-4-pyridin-3-ylmethyl-benzothi...) Show SMILES Cc1c(O)c(C)c2sc(N)nc2c1Cc1cccnc1 Show InChI InChI=1S/C15H15N3OS/c1-8-11(6-10-4-3-5-17-7-10)12-14(9(2)13(8)19)20-15(16)18-12/h3-5,7,19H,6H2,1-2H3,(H2,16,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50173167 ((S)-(2-(4-fluorophenyl)-3-(2-(propylamino)pyrimidi...) Show SMILES CCCNc1nccc(n1)-c1c(nc2CC[C@@H](CO)n12)-c1ccc(F)cc1 Show InChI InChI=1S/C20H22FN5O/c1-2-10-22-20-23-11-9-16(24-20)19-18(13-3-5-14(21)6-4-13)25-17-8-7-15(12-27)26(17)19/h3-6,9,11,15,27H,2,7-8,10,12H2,1H3,(H,22,23,24)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50173169 (CHEMBL383799 | [(R)-2-(4-Fluoro-phenyl)-3-(2-propy...) Show SMILES CCCNc1nccc(n1)-c1c(nc2CC[C@H](CO)n12)-c1ccc(F)cc1 Show InChI InChI=1S/C20H22FN5O/c1-2-10-22-20-23-11-9-16(24-20)19-18(13-3-5-14(21)6-4-13)25-17-8-7-15(12-27)26(17)19/h3-6,9,11,15,27H,2,7-8,10,12H2,1H3,(H,22,23,24)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50037037 (5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...) Show SMILES CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 Show InChI InChI=1S/C16H17N3OS/c1-9-12(7-11-5-4-6-18-8-11)13-15(10(2)14(9)20)21-16(17-3)19-13/h4-6,8,20H,7H2,1-3H3,(H,17,19)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human platelets				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50037040 (2-Ethylamino-5,7-dimethyl-4-pyridin-3-ylmethyl-ben...) Show SMILES CCNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 Show InChI InChI=1S/C17H19N3OS/c1-4-19-17-20-14-13(8-12-6-5-7-18-9-12)10(2)15(21)11(3)16(14)22-17/h5-7,9,21H,4,8H2,1-3H3,(H,19,20)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human platelets				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50173173 (CHEMBL383348 | {4-[(S)-2-(4-Fluoro-phenyl)-5-(4-me...) Show SMILES CCCNc1nccc(n1)-c1c(nc2CC[C@@H](COCc3ccc(OC)cc3)n12)-c1ccc(F)cc1 Show InChI InChI=1S/C28H30FN5O2/c1-3-15-30-28-31-16-14-24(32-28)27-26(20-6-8-21(29)9-7-20)33-25-13-10-22(34(25)27)18-36-17-19-4-11-23(35-2)12-5-19/h4-9,11-12,14,16,22H,3,10,13,15,17-18H2,1-2H3,(H,30,31,32)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.9	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50173167 ((S)-(2-(4-fluorophenyl)-3-(2-(propylamino)pyrimidi...) Show SMILES CCCNc1nccc(n1)-c1c(nc2CC[C@@H](CO)n12)-c1ccc(F)cc1 Show InChI InChI=1S/C20H22FN5O/c1-2-10-22-20-23-11-9-16(24-20)19-18(13-3-5-14(21)6-4-13)25-17-8-7-15(12-27)26(17)19/h3-6,9,11,15,27H,2,7-8,10,12H2,1H3,(H,22,23,24)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against p38 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50037044 (4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylami...) Show SMILES Cc1c(C)c2nc(NCc3ccc(cc3)S(N)(=O)=O)sc2c(C)c1O Show InChI InChI=1S/C17H19N3O3S2/c1-9-10(2)15(21)11(3)16-14(9)20-17(24-16)19-8-12-4-6-13(7-5-12)25(18,22)23/h4-7,21H,8H2,1-3H3,(H,19,20)(H2,18,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50173169 (CHEMBL383799 | [(R)-2-(4-Fluoro-phenyl)-3-(2-propy...) Show SMILES CCCNc1nccc(n1)-c1c(nc2CC[C@H](CO)n12)-c1ccc(F)cc1 Show InChI InChI=1S/C20H22FN5O/c1-2-10-22-20-23-11-9-16(24-20)19-18(13-3-5-14(21)6-4-13)25-17-8-7-15(12-27)26(17)19/h3-6,9,11,15,27H,2,7-8,10,12H2,1H3,(H,22,23,24)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against p38 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50173166 (CHEMBL371720 | N-{3-[4-(3-Azido-phenyl)-5-pyridin-...) Show SMILES Ic1ccc(cc1)C(=O)NCCCn1cnc(c1-c1ccncc1)-c1cccc(c1)N=[N+]=[N-] Show InChI InChI=1S/C24H20IN7O/c25-20-7-5-18(6-8-20)24(33)28-11-2-14-32-16-29-22(23(32)17-9-12-27-13-10-17)19-3-1-4-21(15-19)30-31-26/h1,3-10,12-13,15-16H,2,11,14H2,(H,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory concentration against p38 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50173173 (CHEMBL383348 | {4-[(S)-2-(4-Fluoro-phenyl)-5-(4-me...) Show SMILES CCCNc1nccc(n1)-c1c(nc2CC[C@@H](COCc3ccc(OC)cc3)n12)-c1ccc(F)cc1 Show InChI InChI=1S/C28H30FN5O2/c1-3-15-30-28-31-16-14-24(32-28)27-26(20-6-8-21(29)9-7-20)33-25-13-10-22(34(25)27)18-36-17-19-4-11-23(35-2)12-5-19/h4-9,11-12,14,16,22H,3,10,13,15,17-18H2,1-2H3,(H,30,31,32)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against p38 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50173168 (4-[(S)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...) Show SMILES COc1ccc(COC[C@@H]2CCc3nc(c(-c4ccnc(N)n4)n23)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H24FN5O2/c1-32-20-9-2-16(3-10-20)14-33-15-19-8-11-22-30-23(17-4-6-18(26)7-5-17)24(31(19)22)21-12-13-28-25(27)29-21/h2-7,9-10,12-13,19H,8,11,14-15H2,1H3,(H2,27,28,29)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	61.2	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037036 (5,7-Dimethoxy-2-[(pyridin-3-ylmethyl)-amino]-benzo...) Show SMILES COc1cc2nc(NCc3cccnc3)sc2c(OC)c1O Show InChI InChI=1S/C15H15N3O3S/c1-20-11-6-10-14(13(21-2)12(11)19)22-15(18-10)17-8-9-4-3-5-16-7-9/h3-7,19H,8H2,1-2H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037051 (5,7-Dimethyl-2-propylamino-4-pyridin-3-ylmethyl-be...) Show SMILES CCCNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 Show InChI InChI=1S/C18H21N3OS/c1-4-7-20-18-21-15-14(9-13-6-5-8-19-10-13)11(2)16(22)12(3)17(15)23-18/h5-6,8,10,22H,4,7,9H2,1-3H3,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037037 (5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...) Show SMILES CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 Show InChI InChI=1S/C16H17N3OS/c1-9-12(7-11-5-4-6-18-8-11)13-15(10(2)14(9)20)21-16(17-3)19-13/h4-6,8,20H,7H2,1-3H3,(H,17,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037037 (5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...) Show SMILES CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 Show InChI InChI=1S/C16H17N3OS/c1-9-12(7-11-5-4-6-18-8-11)13-15(10(2)14(9)20)21-16(17-3)19-13/h4-6,8,20H,7H2,1-3H3,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037040 (2-Ethylamino-5,7-dimethyl-4-pyridin-3-ylmethyl-ben...) Show SMILES CCNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 Show InChI InChI=1S/C17H19N3OS/c1-4-19-17-20-14-13(8-12-6-5-7-18-9-12)10(2)15(21)11(3)16(14)22-17/h5-7,9,21H,4,8H2,1-3H3,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037046 (2-Amino-5-methoxy-7-methyl-4-pyridin-3-ylmethyl-be...) Show SMILES COc1c(O)c(C)c2sc(N)nc2c1Cc1cccnc1 Show InChI InChI=1S/C15H15N3O2S/c1-8-12(19)13(20-2)10(6-9-4-3-5-17-7-9)11-14(8)21-15(16)18-11/h3-5,7,19H,6H2,1-2H3,(H2,16,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50173172 (4-[(R)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...) Show SMILES COc1ccc(COC[C@H]2CCc3nc(c(-c4ccnc(N)n4)n23)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H24FN5O2/c1-32-20-9-2-16(3-10-20)14-33-15-19-8-11-22-30-23(17-4-6-18(26)7-5-17)24(31(19)22)21-12-13-28-25(27)29-21/h2-7,9-10,12-13,19H,8,11,14-15H2,1H3,(H2,27,28,29)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against p38 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50173171 (CHEMBL199247 | N-(3-(4-(4-fluorophenyl)-5-(pyridin...) Show SMILES Fc1ccc(cc1)-c1ncn(CCCNC(=O)c2ccccc2)c1-c1ccncc1 Show InChI InChI=1S/C24H21FN4O/c25-21-9-7-18(8-10-21)22-23(19-11-14-26-15-12-19)29(17-28-22)16-4-13-27-24(30)20-5-2-1-3-6-20/h1-3,5-12,14-15,17H,4,13,16H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory concentration against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037041 (2-Amino-7-ethyl-5-methoxy-4-pyridin-3-ylmethyl-ben...) Show SMILES CCc1c(O)c(OC)c(Cc2cccnc2)c2nc(N)sc12 Show InChI InChI=1S/C16H17N3O2S/c1-3-10-13(20)14(21-2)11(7-9-5-4-6-18-8-9)12-15(10)22-16(17)19-12/h4-6,8,20H,3,7H2,1-2H3,(H2,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037045 (5-Methoxy-7-methyl-2-methylamino-4-pyridin-3-ylmet...) Show SMILES CNc1nc2c(Cc3cccnc3)c(OC)c(O)c(C)c2s1 Show InChI InChI=1S/C16H17N3O2S/c1-9-13(20)14(21-3)11(7-10-5-4-6-18-8-10)12-15(9)22-16(17-2)19-12/h4-6,8,20H,7H2,1-3H3,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037046 (2-Amino-5-methoxy-7-methyl-4-pyridin-3-ylmethyl-be...) Show SMILES COc1c(O)c(C)c2sc(N)nc2c1Cc1cccnc1 Show InChI InChI=1S/C15H15N3O2S/c1-8-12(19)13(20-2)10(6-9-4-3-5-17-7-9)11-14(8)21-15(16)18-11/h3-5,7,19H,6H2,1-2H3,(H2,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037041 (2-Amino-7-ethyl-5-methoxy-4-pyridin-3-ylmethyl-ben...) Show SMILES CCc1c(O)c(OC)c(Cc2cccnc2)c2nc(N)sc12 Show InChI InChI=1S/C16H17N3O2S/c1-3-10-13(20)14(21-2)11(7-9-5-4-6-18-8-9)12-15(10)22-16(17)19-12/h4-6,8,20H,3,7H2,1-2H3,(H2,17,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037039 (2-Amino-5,7-dimethyl-4-pyridin-3-ylmethyl-benzothi...) Show SMILES Cc1c(O)c(C)c2sc(N)nc2c1Cc1cccnc1 Show InChI InChI=1S/C15H15N3OS/c1-8-11(6-10-4-3-5-17-7-10)12-14(9(2)13(8)19)20-15(16)18-12/h3-5,7,19H,6H2,1-2H3,(H2,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50037037 (5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...) Show SMILES CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 Show InChI InChI=1S/C16H17N3OS/c1-9-12(7-11-5-4-6-18-8-11)13-15(10(2)14(9)20)21-16(17-3)19-13/h4-6,8,20H,7H2,1-3H3,(H,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophils				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037044 (4-[(6-Hydroxy-4,5,7-trimethyl-benzothiazol-2-ylami...) Show SMILES Cc1c(C)c2nc(NCc3ccc(cc3)S(N)(=O)=O)sc2c(C)c1O Show InChI InChI=1S/C17H19N3O3S2/c1-9-10(2)15(21)11(3)16-14(9)20-17(24-16)19-8-12-4-6-13(7-5-12)25(18,22)23/h4-7,21H,8H2,1-3H3,(H,19,20)(H2,18,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cells				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50173170 (CHEMBL198261 | {4-[(R)-2-(4-Fluoro-phenyl)-5-(4-me...) Show SMILES CCCNc1nccc(n1)-c1c(nc2CC[C@H](COCc3ccc(OC)cc3)n12)-c1ccc(F)cc1 Show InChI InChI=1S/C28H30FN5O2/c1-3-15-30-28-31-16-14-24(32-28)27-26(20-6-8-21(29)9-7-20)33-25-13-10-22(34(25)27)18-36-17-19-4-11-23(35-2)12-5-19/h4-9,11-12,14,16,22H,3,10,13,15,17-18H2,1-2H3,(H,30,31,32)/t22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	217	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against p38 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037037 (5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-be...) Show SMILES CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 Show InChI InChI=1S/C16H17N3OS/c1-9-12(7-11-5-4-6-18-8-11)13-15(10(2)14(9)20)21-16(17-3)19-13/h4-6,8,20H,7H2,1-3H3,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cells				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037038 (2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...) Show SMILES CCNc1nc2c(C)c(Cc3cccnc3)c(O)c(C)c2s1 Show InChI InChI=1S/C17H19N3OS/c1-4-19-17-20-14-10(2)13(8-12-6-5-7-18-9-12)15(21)11(3)16(14)22-17/h5-7,9,21H,4,8H2,1-3H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50173170 (CHEMBL198261 | {4-[(R)-2-(4-Fluoro-phenyl)-5-(4-me...) Show SMILES CCCNc1nccc(n1)-c1c(nc2CC[C@H](COCc3ccc(OC)cc3)n12)-c1ccc(F)cc1 Show InChI InChI=1S/C28H30FN5O2/c1-3-15-30-28-31-16-14-24(32-28)27-26(20-6-8-21(29)9-7-20)33-25-13-10-22(34(25)27)18-36-17-19-4-11-23(35-2)12-5-19/h4-9,11-12,14,16,22H,3,10,13,15,17-18H2,1-2H3,(H,30,31,32)/t22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037047 (2-Amino-4,5-dimethyl-7-pyridin-3-ylmethyl-benzothi...) Show SMILES Cc1c(C)c2nc(N)sc2c(Cc2cccnc2)c1O Show InChI InChI=1S/C15H15N3OS/c1-8-9(2)13(19)11(6-10-4-3-5-17-7-10)14-12(8)18-15(16)20-14/h3-5,7,19H,6H2,1-2H3,(H2,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50173172 (4-[(R)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...) Show SMILES COc1ccc(COC[C@H]2CCc3nc(c(-c4ccnc(N)n4)n23)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H24FN5O2/c1-32-20-9-2-16(3-10-20)14-33-15-19-8-11-22-30-23(17-4-6-18(26)7-5-17)24(31(19)22)21-12-13-28-25(27)29-21/h2-7,9-10,12-13,19H,8,11,14-15H2,1H3,(H2,27,28,29)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037043 (2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...) Show SMILES CCNc1nc2c(C)c(C)c(O)c(Cc3cccnc3)c2s1 Show InChI InChI=1S/C17H19N3OS/c1-4-19-17-20-14-10(2)11(3)15(21)13(16(14)22-17)8-12-6-5-7-18-9-12/h5-7,9,21H,4,8H2,1-3H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cells				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50173168 (4-[(S)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...) Show SMILES COc1ccc(COC[C@@H]2CCc3nc(c(-c4ccnc(N)n4)n23)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H24FN5O2/c1-32-20-9-2-16(3-10-20)14-33-15-19-8-11-22-30-23(17-4-6-18(26)7-5-17)24(31(19)22)21-12-13-28-25(27)29-21/h2-7,9-10,12-13,19H,8,11,14-15H2,1H3,(H2,27,28,29)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibitory activity against p38 at a concentration of 1.0 uM				Bioorg Med Chem Lett 15: 4666-70 (2005) Article DOI: 10.1016/j.bmcl.2005.07.076 BindingDB Entry DOI: 10.7270/Q28G8K8K
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037053 (4,7-Dimethyl-2-methylamino-5-pyridin-3-ylmethyl-be...) Show SMILES CNc1nc2c(C)c(Cc3cccnc3)c(O)c(C)c2s1 Show InChI InChI=1S/C16H17N3OS/c1-9-12(7-11-5-4-6-18-8-11)14(20)10(2)15-13(9)19-16(17-3)21-15/h4-6,8,20H,7H2,1-3H3,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037048 (7-Ethyl-5-methoxy-2-methylamino-4-pyridin-3-ylmeth...) Show SMILES CCc1c(O)c(OC)c(Cc2cccnc2)c2nc(NC)sc12 Show InChI InChI=1S/C17H19N3O2S/c1-4-11-14(21)15(22-3)12(8-10-6-5-7-19-9-10)13-16(11)23-17(18-2)20-13/h5-7,9,21H,4,8H2,1-3H3,(H,18,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50037038 (2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...) Show SMILES CCNc1nc2c(C)c(Cc3cccnc3)c(O)c(C)c2s1 Show InChI InChI=1S/C17H19N3OS/c1-4-19-17-20-14-10(2)13(8-12-6-5-7-18-9-12)15(21)11(3)16(14)22-17/h5-7,9,21H,4,8H2,1-3H3,(H,19,20)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human platelets				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description In vitro activities of Leukotriene B4 receptor (LTB4) in human neutrophils				J Med Chem 39: 3148-57 (1996) Article DOI: 10.1021/jm950725r BindingDB Entry DOI: 10.7270/Q2R2121S
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037038 (2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...) Show SMILES CCNc1nc2c(C)c(Cc3cccnc3)c(O)c(C)c2s1 Show InChI InChI=1S/C17H19N3OS/c1-4-19-17-20-14-10(2)13(8-12-6-5-7-18-9-12)15(21)11(3)16(14)22-17/h5-7,9,21H,4,8H2,1-3H3,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50037043 (2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...) Show SMILES CCNc1nc2c(C)c(C)c(O)c(Cc3cccnc3)c2s1 Show InChI InChI=1S/C17H19N3OS/c1-4-19-17-20-14-10(2)11(3)15(21)13(16(14)22-17)8-12-6-5-7-18-9-12/h5-7,9,21H,4,8H2,1-3H3,(H,19,20)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human platelets				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037040 (2-Ethylamino-5,7-dimethyl-4-pyridin-3-ylmethyl-ben...) Show SMILES CCNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 Show InChI InChI=1S/C17H19N3OS/c1-4-19-17-20-14-13(8-12-6-5-7-18-9-12)10(2)15(21)11(3)16(14)22-17/h5-7,9,21H,4,8H2,1-3H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cells				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037045 (5-Methoxy-7-methyl-2-methylamino-4-pyridin-3-ylmet...) Show SMILES CNc1nc2c(Cc3cccnc3)c(OC)c(O)c(C)c2s1 Show InChI InChI=1S/C16H17N3O2S/c1-9-13(20)14(21-3)11(7-10-5-4-6-18-8-10)12-15(9)22-16(17-2)19-12/h4-6,8,20H,7H2,1-3H3,(H,17,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037050 (4-Phenyl-2-[(pyridin-3-ylmethyl)-amino]-benzothiaz...) Show SMILES Oc1cc(-c2ccccc2)c2nc(NCc3cccnc3)sc2c1 Show InChI InChI=1S/C19H15N3OS/c23-15-9-16(14-6-2-1-3-7-14)18-17(10-15)24-19(22-18)21-12-13-5-4-8-20-11-13/h1-11,23H,12H2,(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50037042 (4-Methyl-2-[(pyridin-3-ylmethyl)-amino]-naphtho[1,...) Show SMILES Cc1c(O)c2ccccc2c2nc(NCc3cccnc3)sc12 Show InChI InChI=1S/C18H15N3OS/c1-11-16(22)14-7-3-2-6-13(14)15-17(11)23-18(21-15)20-10-12-5-4-8-19-9-12/h2-9,22H,10H2,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037049 (4,5,7-Trimethyl-2-[(pyridin-3-ylmethyl)-amino]-ben...) Show SMILES Cc1c(C)c2nc(NCc3cccnc3)sc2c(C)c1O Show InChI InChI=1S/C16H17N3OS/c1-9-10(2)14(20)11(3)15-13(9)19-16(21-15)18-8-12-5-4-6-17-7-12/h4-7,20H,8H2,1-3H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037043 (2-Ethylamino-4,5-dimethyl-7-pyridin-3-ylmethyl-ben...) Show SMILES CCNc1nc2c(C)c(C)c(O)c(Cc3cccnc3)c2s1 Show InChI InChI=1S/C17H19N3OS/c1-4-19-17-20-14-10(2)11(3)15(21)13(16(14)22-17)8-12-6-5-7-18-9-12/h5-7,9,21H,4,8H2,1-3H3,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037042 (4-Methyl-2-[(pyridin-3-ylmethyl)-amino]-naphtho[1,...) Show SMILES Cc1c(O)c2ccccc2c2nc(NCc3cccnc3)sc12 Show InChI InChI=1S/C18H15N3OS/c1-11-16(22)14-7-3-2-6-13(14)15-17(11)23-18(21-15)20-10-12-5-4-8-19-9-12/h2-9,22H,10H2,1H3,(H,20,21)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037052 (4,7-Dimethyl-2-[(pyridin-3-ylmethyl)-amino]-benzot...) Show SMILES Cc1cc(O)c(C)c2sc(NCc3cccnc3)nc12 Show InChI InChI=1S/C15H15N3OS/c1-9-6-12(19)10(2)14-13(9)18-15(20-14)17-8-11-4-3-5-16-7-11/h3-7,19H,8H2,1-2H3,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Rattus norvegicus)	BDBM50037047 (2-Amino-4,5-dimethyl-7-pyridin-3-ylmethyl-benzothi...) Show SMILES Cc1c(C)c2nc(N)sc2c(Cc2cccnc2)c1O Show InChI InChI=1S/C15H15N3OS/c1-8-9(2)13(19)11(6-10-4-3-5-17-7-10)14-12(8)18-15(16)20-14/h3-5,7,19H,6H2,1-2H3,(H2,16,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat				J Med Chem 37: 3062-70 (1994) BindingDB Entry DOI: 10.7270/Q2WM1F2J
					More data for this Ligand-Target Pair

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