Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 3A/3B | ||
Ligand | BDBM50076408 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_3232 (CHEMBL618918) | ||
Ki | 0.70±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 3A/3B | |||
Name: | 5-hydroxytryptamine receptor 3A/3B | ||
Synonyms: | Serotonin 3 (5-HT3) receptor | Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor | ||
Type: | n/a | ||
Mol. Mass.: | n/a | ||
Description: | ASSAY_ID of EBI is 2974 | ||
Components: | This complex has 2 components. | ||
Component 1 | |||
Name: | 5-hydroxytryptamine receptor 3B | ||
Synonyms: | 5HT3B_RAT | Htr3b | Serotonin (5-HT) receptor | ||
Type: | PROTEIN | ||
Mol. Mass.: | 50328.78 | ||
Organism: | Rattus norvegicus | ||
Description: | EBI_11885 | ||
Residue: | 437 | ||
Sequence: |
| ||
Component 2 | |||
Name: | 5-hydroxytryptamine receptor 3A | ||
Synonyms: | 5-HT3 | 5-hydroxytryptamine receptor 3A | 5HT3A_RAT | 5ht3 | Htr3 | Htr3a | Serotonin (5-HT) receptor | Zacopride site-R | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 55428.70 | ||
Organism: | RAT | ||
Description: | 5-HT3 HTR3A RAT::P35563 | ||
Residue: | 483 | ||
Sequence: |
| ||
BDBM50076408 | |||
n/a | |||
Name | BDBM50076408 | ||
Synonyms: | 4-(2-Fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)-3-[2-(tetrahydro-furan-2-yloxy)-ethyl]-quinoline | CHEMBL289664 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H30FN3O2 | ||
Mol. Mass. | 435.5337 | ||
SMILES | CN1CCN(CC1)c1nc2ccccc2c(c1CCOC1CCCO1)-c1ccccc1F |(19.39,-9.64,;18.06,-8.87,;18.06,-7.32,;16.71,-6.51,;15.38,-7.32,;15.38,-8.87,;16.72,-9.64,;14.04,-6.56,;12.7,-7.35,;11.36,-6.56,;10.01,-7.35,;8.68,-6.58,;8.68,-5.02,;10.01,-4.25,;11.36,-5.02,;12.69,-4.24,;14.02,-5,;15.35,-4.23,;16.7,-4.98,;18.03,-4.21,;19.36,-4.95,;19.54,-6.48,;21.04,-6.79,;21.81,-5.44,;20.76,-4.31,;12.67,-2.71,;14,-1.94,;14,-.4,;12.66,.37,;11.32,-.43,;11.34,-1.96,;10.01,-2.75,)| | ||
Structure | ![]() |