| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50065791 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90579 (CHEMBL701163) |
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| IC50 | >100000.00±n/a nM |
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| Citation |  Ouali, M; Laboulais, C; Leh, H; Gill, D; Desmaële, D; Mekouar, K; Zouhiri, F; d'Angelo, J; Auclair, C; Mouscadet, JF; Le Bret, M Modeling of the inhibition of retroviral integrases by styrylquinoline derivatives. J Med Chem43:1949-57 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50065791 |
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| n/a |
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| Name | BDBM50065791 |
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| Synonyms: | 4-[(E)-2-(8-Amino-quinolin-2-yl)-vinyl]-benzene-1,2-diol | 4-[2-(8-Amino-quinolin-2-yl)-vinyl]-benzene-1,2-diol | CHEMBL58191 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N2O2 |
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| Mol. Mass. | 278.3053 |
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| SMILES | Nc1cccc2ccc(\C=C\c3ccc(O)c(O)c3)nc12 |
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| Structure | 
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