Compile Data Set for Download or QSAR

Found 139 hits with Last Name = 'd''angelo' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50065797 (CHEMBL329488 | Sodium; 8-hydroxy-2-[(E)-2-(3,4,5-t...) Show SMILES Oc1cc(\C=C\c2ccc3ccc(C([O-])=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C18H13NO6/c20-13-7-9(8-14(21)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)19-11/h1-8,20-23H,(H,24,25)/p-1/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description HIV integrase inhibitory potency of the compound was evaluated as IC50 on 3' processing of target DNA.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065793 (8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO6/c20-13-7-9(8-14(21)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)19-11/h1-8,20-23H,(H,24,25)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description HIV integrase inhibitory potency of the compound was evaluated as IC50 on 3' processing of target DNA.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065793 (8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO6/c20-13-7-9(8-14(21)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)19-11/h1-8,20-23H,(H,24,25)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065793 (8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO6/c20-13-7-9(8-14(21)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)19-11/h1-8,20-23H,(H,24,25)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8532 Curated by ChEMBL					Assay Description Inhibition of human immunodeficiency virus-1 (HIV-1) integrase.				J Med Chem 43: 1949-57 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2RB759N
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065793 (8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO6/c20-13-7-9(8-14(21)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)19-11/h1-8,20-23H,(H,24,25)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065793 (8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO6/c20-13-7-9(8-14(21)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)19-11/h1-8,20-23H,(H,24,25)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description In vitro anti-HIV integrase activity of the compound was tested against integration(strand transfer) of target plasmid.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065788 ((E)-2-(3-carboxy-4-hydroxystyryl)-8-hydroxyquinoli...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(c3)C(O)=O)nc2c1O Show InChI InChI=1S/C19H13NO6/c21-15-8-2-10(9-14(15)19(25)26)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)20-12/h1-9,21-22H,(H,23,24)(H,25,26)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description In vitro anti-HIV integrase activity of the compound was tested against integration(strand transfer) of target plasmid.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/b5-2+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50483192 (CHEMBL1631331) Show SMILES [Na;v0+].[#6]-[#8]-c1cc(\[#6]=[#6]\c2ccc3ccc(-[#6](-[#8-])=O)c(-[#8])c3n2)cc(-[#8])c1-[#8] Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/p-1/b5-2+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Lyon 1 Curated by ChEMBL					Assay Description Inhibition of HIV 1 integrase strand transfer activity				Antimicrob Agents Chemother 52: 3532-41 (2008) Article DOI: 10.1128/AAC.01361-07 BindingDB Entry DOI: 10.7270/Q26976D3
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/b5-2+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8076 Curated by ChEMBL					Assay Description In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.				Bioorg Med Chem Lett 14: 2473-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.005 BindingDB Entry DOI: 10.7270/Q2RX9BH1
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065795 (CHEMBL100082 | Sodium; 2-[(E)-2-(3,4-dihydroxy-phe...) Show SMILES Oc1ccc(\C=C\c2ccc3ccc(C([O-])=O)c(O)c3n2)cc1O Show InChI InChI=1S/C18H13NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/p-1/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description HIV integrase inhibitory potency of the compound was evaluated as IC50 on 3' processing of target DNA.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087427 ((E)-8-hydroxy-2-(3-hydroxy-4-methoxystyryl)quinoli...) Show SMILES COc1ccc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc1O Show InChI InChI=1S/C19H15NO5/c1-25-16-9-3-11(10-15(16)21)2-6-13-7-4-12-5-8-14(19(23)24)18(22)17(12)20-13/h2-10,21-22H,1H3,(H,23,24)/b6-2+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50145369 (2-(3,4-Dihydroxy-phenylcarbamoyl)-8-hydroxy-quinol...) Show SMILES OC(=O)c1ccc2ccc(nc2c1O)C(=O)Nc1ccc(O)c(O)c1 Show InChI InChI=1S/C17H12N2O6/c20-12-6-3-9(7-13(12)21)18-16(23)11-5-2-8-1-4-10(17(24)25)15(22)14(8)19-11/h1-7,20-22H,(H,18,23)(H,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8076 Curated by ChEMBL					Assay Description In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.				Bioorg Med Chem Lett 14: 2473-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.005 BindingDB Entry DOI: 10.7270/Q2RX9BH1
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50065796 ((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Unité Associée au CNRS Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HIV-1 recombinant integrase activity in strand transfer assay				Bioorg Med Chem Lett 15: 4019-22 (2005) Article DOI: 10.1016/j.bmcl.2005.06.036 BindingDB Entry DOI: 10.7270/Q2GM86VW
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065796 ((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065796 ((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description In vitro anti-HIV integrase activity of the compound was tested against integration(strand transfer) of target plasmid.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087431 (2-[2-(4-Acetylamino-phenyl)-vinyl]-8-hydroxy-quino...) Show SMILES CC(=O)Nc1ccc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc1 Show InChI InChI=1S/C20H16N2O4/c1-12(23)21-15-7-2-13(3-8-15)4-9-16-10-5-14-6-11-17(20(25)26)19(24)18(14)22-16/h2-11,24H,1H3,(H,21,23)(H,25,26)/b9-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087432 (8-Hydroxy-2-[2-(4-nitro-phenyl)-vinyl]-quinoline-7...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(cc3)[N+]([O-])=O)nc2c1O Show InChI InChI=1S/C18H12N2O5/c21-17-15(18(22)23)10-5-12-4-7-13(19-16(12)17)6-1-11-2-8-14(9-3-11)20(24)25/h1-10,21H,(H,22,23)/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087429 ((E)-2-(3,5-dibromo-4-hydroxystyryl)-8-hydroxyquino...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(Br)c(O)c(Br)c3)nc2c1O Show InChI InChI=1S/C18H11Br2NO4/c19-13-7-9(8-14(20)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)21-11/h1-8,22-23H,(H,24,25)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087429 ((E)-2-(3,5-dibromo-4-hydroxystyryl)-8-hydroxyquino...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(Br)c(O)c(Br)c3)nc2c1O Show InChI InChI=1S/C18H11Br2NO4/c19-13-7-9(8-14(20)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)21-11/h1-8,22-23H,(H,24,25)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087431 (2-[2-(4-Acetylamino-phenyl)-vinyl]-8-hydroxy-quino...) Show SMILES CC(=O)Nc1ccc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc1 Show InChI InChI=1S/C20H16N2O4/c1-12(23)21-15-7-2-13(3-8-15)4-9-16-10-5-14-6-11-17(20(25)26)19(24)18(14)22-16/h2-11,24H,1H3,(H,21,23)(H,25,26)/b9-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50145363 (8-Hydroxy-2-(2,3,4-trihydroxy-benzylcarbamoyl)-qui...) Show SMILES OC(=O)c1ccc2ccc(nc2c1O)C(=O)NCc1ccc(O)c(O)c1O Show InChI InChI=1S/C18H14N2O7/c21-12-6-3-9(14(22)16(12)24)7-19-17(25)11-5-2-8-1-4-10(18(26)27)15(23)13(8)20-11/h1-6,21-24H,7H2,(H,19,25)(H,26,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8076 Curated by ChEMBL					Assay Description In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.				Bioorg Med Chem Lett 14: 2473-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.005 BindingDB Entry DOI: 10.7270/Q2RX9BH1
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087426 (2-(3,4-dihydroxyphenethyl)-8-hydroxyquinoline-7-ca...) Show SMILES OC(=O)c1ccc2ccc(CCc3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H15NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h2-4,6-9,20-22H,1,5H2,(H,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087435 ((E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carbo...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3)nc2c1O Show InChI InChI=1S/C18H13NO4/c20-14-8-2-11(3-9-14)1-6-13-7-4-12-5-10-15(18(22)23)17(21)16(12)19-13/h1-10,20-21H,(H,22,23)/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087435 ((E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carbo...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3)nc2c1O Show InChI InChI=1S/C18H13NO4/c20-14-8-2-11(3-9-14)1-6-13-7-4-12-5-10-15(18(22)23)17(21)16(12)19-13/h1-10,20-21H,(H,22,23)/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087419 ((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O Show InChI InChI=1S/C19H15NO6/c1-26-15-9-10(8-14(21)18(15)23)2-5-12-6-3-11-4-7-13(19(24)25)17(22)16(11)20-12/h2-9,21-23H,1H3,(H,24,25)/b5-2+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087432 (8-Hydroxy-2-[2-(4-nitro-phenyl)-vinyl]-quinoline-7...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(cc3)[N+]([O-])=O)nc2c1O Show InChI InChI=1S/C18H12N2O5/c21-17-15(18(22)23)10-5-12-4-7-13(19-16(12)17)6-1-11-2-8-14(9-3-11)20(24)25/h1-10,21H,(H,22,23)/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087430 ((E)-2-(2-(furan-2-yl)vinyl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccco3)nc2c1O Show InChI InChI=1S/C16H11NO4/c18-15-13(16(19)20)8-4-10-3-5-11(17-14(10)15)6-7-12-2-1-9-21-12/h1-9,18H,(H,19,20)/b7-6+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing was tested in CEM cells				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50065796 ((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Unité Associée au CNRS Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HIV-1 recombinant integrase activity in standard 3'-processing assay				Bioorg Med Chem Lett 15: 4019-22 (2005) Article DOI: 10.1016/j.bmcl.2005.06.036 BindingDB Entry DOI: 10.7270/Q2GM86VW
					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Rous sarcoma virus (strain Prague C) (RSV-PrC))	BDBM50065793 (8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)c(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO6/c20-13-7-9(8-14(21)17(13)23)1-4-11-5-2-10-3-6-12(18(24)25)16(22)15(10)19-11/h1-8,20-23H,(H,24,25)/b4-1+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8532 Curated by ChEMBL					Assay Description Inhibition of rous sarcoma virus (RSV) Integrase.				J Med Chem 43: 1949-57 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2RB759N
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087421 (8-Hydroxy-2-((E)-styryl)-quinoline-7-carboxylic ac...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccccc3)nc2c1O Show InChI InChI=1S/C18H13NO3/c20-17-15(18(21)22)11-8-13-7-10-14(19-16(13)17)9-6-12-4-2-1-3-5-12/h1-11,20H,(H,21,22)/b9-6+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065783 (5-(2-{7-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy...) Show SMILES Oc1ccc(\C=C\c2ccc3ccc(\C=C\c4ccc(O)c(O)c4)c(O)c3n2)cc1O Show InChI InChI=1S/C25H19NO5/c27-20-11-3-15(13-22(20)29)1-5-18-7-6-17-8-10-19(26-24(17)25(18)31)9-2-16-4-12-21(28)23(30)14-16/h1-14,27-31H/b5-1+,9-2+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description HIV integrase inhibitory potency of the compound was evaluated as IC50 on 3' processing of target DNA.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087420 ((E)-2-(4-aminostyryl)-8-hydroxyquinoline-7-carboxy...) Show SMILES Nc1ccc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc1 Show InChI InChI=1S/C18H14N2O3/c19-13-6-1-11(2-7-13)3-8-14-9-4-12-5-10-15(18(22)23)17(21)16(12)20-14/h1-10,21H,19H2,(H,22,23)/b8-3+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087426 (2-(3,4-dihydroxyphenethyl)-8-hydroxyquinoline-7-ca...) Show SMILES OC(=O)c1ccc2ccc(CCc3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H15NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h2-4,6-9,20-22H,1,5H2,(H,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Rous sarcoma virus (strain Prague C) (RSV-PrC))	BDBM50065796 ((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8532 Curated by ChEMBL					Assay Description Inhibition of rous sarcoma virus (RSV) Integrase.				J Med Chem 43: 1949-57 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2RB759N
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087426 (2-(3,4-dihydroxyphenethyl)-8-hydroxyquinoline-7-ca...) Show SMILES OC(=O)c1ccc2ccc(CCc3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H15NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h2-4,6-9,20-22H,1,5H2,(H,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8076 Curated by ChEMBL					Assay Description In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.				Bioorg Med Chem Lett 14: 2473-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.005 BindingDB Entry DOI: 10.7270/Q2RX9BH1
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065796 ((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8076 Curated by ChEMBL					Assay Description In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.				Bioorg Med Chem Lett 14: 2473-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.005 BindingDB Entry DOI: 10.7270/Q2RX9BH1
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065796 ((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description HIV integrase inhibitory potency of the compound was evaluated as IC50 on 3' processing of target DNA.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065787 (4-(2-(8-hydroxyquinolin-2-yl)vinyl)benzene-1,2-dio...) Show SMILES Oc1ccc(\C=C\c2ccc3cccc(O)c3n2)cc1O Show InChI InChI=1S/C17H13NO3/c19-14-9-5-11(10-16(14)21)4-7-13-8-6-12-2-1-3-15(20)17(12)18-13/h1-10,19-21H/b7-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description In vitro anti-HIV integrase activity of the compound was tested against integration(strand transfer) of target plasmid.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065796 ((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8532 Curated by ChEMBL					Assay Description Inhibition of human immunodeficiency virus-1 (HIV-1) integrase.				J Med Chem 43: 1949-57 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2RB759N
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065796 ((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(O)c3)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-14-8-2-10(9-15(14)21)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065790 ((E)-2-(2,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3O)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-13-7-3-10(15(21)9-13)1-5-12-6-2-11-4-8-14(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8532 Curated by ChEMBL					Assay Description Inhibition of human immunodeficiency virus-1 (HIV-1) integrase.				J Med Chem 43: 1949-57 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2RB759N
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065788 ((E)-2-(3-carboxy-4-hydroxystyryl)-8-hydroxyquinoli...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(c3)C(O)=O)nc2c1O Show InChI InChI=1S/C19H13NO6/c21-15-8-2-10(9-14(15)19(25)26)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)20-12/h1-9,21-22H,(H,23,24)(H,25,26)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description HIV integrase inhibitory potency of the compound was evaluated as IC50 on 3' processing of target DNA.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50065788 ((E)-2-(3-carboxy-4-hydroxystyryl)-8-hydroxyquinoli...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)c(c3)C(O)=O)nc2c1O Show InChI InChI=1S/C19H13NO6/c21-15-8-2-10(9-14(15)19(25)26)1-5-12-6-3-11-4-7-13(18(23)24)17(22)16(11)20-12/h1-9,21-22H,(H,23,24)(H,25,26)/b5-1+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8532 Curated by ChEMBL					Assay Description Compound was tested in vitro to inhibit human immuno virus-1 (HIV-1) using enzymatic disintegration assay.				J Med Chem 43: 1949-57 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2RB759N
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065790 ((E)-2-(2,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3O)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-13-7-3-10(15(21)9-13)1-5-12-6-2-11-4-8-14(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description In vitro anti-HIV integrase activity of the compound was tested against integration(strand transfer) of target plasmid.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065790 ((E)-2-(2,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3O)nc2c1O Show InChI InChI=1S/C18H13NO5/c20-13-7-3-10(15(21)9-13)1-5-12-6-2-11-4-8-14(18(23)24)17(22)16(11)19-12/h1-9,20-22H,(H,23,24)/b5-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087425 (8-Hydroxy-2-[2-(4-hydroxy-3-methoxy-phenyl)-vinyl]...) Show SMILES COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)ccc1O Show InChI InChI=1S/C19H15NO5/c1-25-16-10-11(3-9-15(16)21)2-6-13-7-4-12-5-8-14(19(23)24)18(22)17(12)20-13/h2-10,21-22H,1H3,(H,23,24)/b6-2+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50145368 (2-(2-(2,4-dinitrophenyl)hydrazinecarbonyl)-8-hydro...) Show SMILES OC(=O)c1ccc2ccc(nc2c1O)C(=O)NNc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C17H11N5O8/c23-15-10(17(25)26)4-1-8-2-5-12(18-14(8)15)16(24)20-19-11-6-3-9(21(27)28)7-13(11)22(29)30/h1-7,19,23H,(H,20,24)(H,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8076 Curated by ChEMBL					Assay Description In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.				Bioorg Med Chem Lett 14: 2473-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.005 BindingDB Entry DOI: 10.7270/Q2RX9BH1
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087434 (8-Hydroxy-2-(2-thiophen-3-yl-vinyl)-quinoline-7-ca...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccsc3)nc2c1O Show InChI InChI=1S/C16H11NO3S/c18-15-13(16(19)20)6-3-11-2-5-12(17-14(11)15)4-1-10-7-8-21-9-10/h1-9,18H,(H,19,20)/b4-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50065786 (2-[(E)-2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-q...) Show SMILES Oc1ccc(\C=C\c2ccc3ccc(C#N)c(O)c3n2)cc1O Show InChI InChI=1S/C18H12N2O3/c19-10-13-4-3-12-5-7-14(20-17(12)18(13)23)6-1-11-2-8-15(21)16(22)9-11/h1-9,21-23H/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description HIV integrase inhibitory potency of the compound was evaluated as IC50 on 3' processing of target DNA.				J Med Chem 41: 2846-57 (1998) Article DOI: 10.1021/jm980043e BindingDB Entry DOI: 10.7270/Q21Z43JH
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 139 total )  |  Next  |  Last  >>

Jump to: