| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50026998 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_147183 (CHEMBL754482) |
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| Ki | 2±n/a nM |
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| Citation |  Schütz, J; Dersch, CM; Horel, R; Spetea, M; Koch, M; Meditz, R; Greiner, E; Rothman, RB; Schmidhammer, H Synthesis and biological evaluation of 14-alkoxymorphinans. 17. Highly delta opioid receptor selective 14-alkoxy-substituted indolo- and benzofuromorphinans. J Med Chem45:5378-83 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40465.04 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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| BDBM50026998 |
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| n/a |
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| Name | BDBM50026998 |
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| Synonyms: | CHEMBL2113662 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H28N2O3 |
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| Mol. Mass. | 428.5228 |
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| SMILES | [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC=C)CC[C@@]14[C@]5(Cc1c2n(C)c2ccccc12)OC)ccc3O |r,THB:10:9:16:6.5.4| |
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| Structure | 
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