| Reaction Details |
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 | Report a problem with these data |
| Target | Putative deoxyuridine triphosphatase |
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| Ligand | BDBM50266744 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_320883 (CHEMBL884808) |
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| Ki | >1000000±n/a nM |
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| Citation |  Nguyen, C; Kasinathan, G; Leal-Cortijo, I; Musso-Buendia, A; Kaiser, M; Brun, R; Ruiz-Pérez, LM; Johansson, NG; González-Pacanowska, D; Gilbert, IH Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. J Med Chem48:5942-54 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Putative deoxyuridine triphosphatase |
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| Name: | Putative deoxyuridine triphosphatase |
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| Synonyms: | dUTP pyrophosphatase | dUTPase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30347.26 |
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| Organism: | Leishmania major |
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| Description: | ChEMBL_320883 |
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| Residue: | 268 |
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| Sequence: | MKRARSANIPGAILHSLAELQDGLNAMIDPSWRAVRSLDNWALAITMESTELLDSYPWKW
WKNLNATPDLANVRIELVDIFHFSLSGAMQMRSTPDDEIPAASLKPLKEVMTTFLPAKEC
TSDPYGFVFFPLTDTQNAIASFRNIIQLANAYRFDVIIECIIYAAEDLGFNLVAYYIAKH
TLNCIRQLSGYKDGSYVKVNNGVEDNSLLHNCIKDVSLDEVLDADKYVQAWNSIMANVYE
AFQIKESDRKDAERWFALAKENRLAIKA
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| BDBM50266744 |
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| n/a |
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| Name | BDBM50266744 |
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| Synonyms: | 1-((2R,4S,5R)-5-((tert-butyldiphenylsilyloxy)methyl)-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | CHEMBL513890 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H30N2O5Si |
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| Mol. Mass. | 466.6016 |
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| SMILES | CC(C)(C)[Si](OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1 |r| |
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| Structure | 
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