| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin G |
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| Ligand | BDBM50270031 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_508148 (CHEMBL1007397) |
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| IC50 | 90±n/a nM |
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| Citation |  Méthot, N; Rubin, J; Guay, D; Beaulieu, C; Ethier, D; Reddy, TJ; Riendeau, D; Percival, MD Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing. J Biol Chem282:20836-46 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin G |
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| Name: | Cathepsin G |
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| Synonyms: | CATG_HUMAN | CG | CTSG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28860.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469016 |
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| Residue: | 255 |
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| Sequence: | MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL
TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR
NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD
PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRT
TMRSFKLLDQMETPL
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| BDBM50270031 |
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| n/a |
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| Name | BDBM50270031 |
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| Synonyms: | 1-((1R,2R)-1-cyano-2-phenylcyclopropylamino)-3-(3-fluorothiophen-2-yl)-1-oxopropan-2-aminium 2,2,2-trifluoroacetate | CHEMBL515494 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17FN3OS |
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| Mol. Mass. | 330.399 |
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| SMILES | [NH3+]C(Cc1sccc1F)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| |
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| Structure | 
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