| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit alpha-2 |
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| Ligand | BDBM50244262 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_491122 (CHEMBL991890) |
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| Ki | 21.4±n/a nM |
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| Citation |  Harris, D; Clayton, T; Cook, J; Sahbaie, P; Halliwell, RF; Furtmüller, R; Huck, S; Sieghart, W; DeLorey, TM Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit. J Med Chem51:3788-803 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gamma-aminobutyric acid receptor subunit alpha-2 |
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| Name: | Gamma-aminobutyric acid receptor subunit alpha-2 |
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| Synonyms: | GABA receptor alpha-2 subunit | GABRA2 | GBRA2_HUMAN | Gamma-aminobutyric acid receptor subunit alpha-2 (GABRA2) |
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| Type: | Protein |
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| Mol. Mass.: | 51338.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47869 |
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| Residue: | 451 |
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| Sequence: | MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
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| BDBM50244262 |
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| n/a |
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| Name | BDBM50244262 |
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| Synonyms: | CHEMBL471978 | ethyl 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]quinazoline-3-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13N3O3 |
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| Mol. Mass. | 295.2927 |
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| SMILES | CCOC(=O)c1ncn2c1n(C)c(=O)c1cc(ccc21)C#C |
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| Structure | 
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