| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit alpha-6 |
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| Ligand | BDBM50244263 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_491125 (CHEMBL991893) |
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| Ki | >1500±n/a nM |
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| Citation |  Harris, D; Clayton, T; Cook, J; Sahbaie, P; Halliwell, RF; Furtmüller, R; Huck, S; Sieghart, W; DeLorey, TM Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit. J Med Chem51:3788-803 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gamma-aminobutyric acid receptor subunit alpha-6 |
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| Name: | Gamma-aminobutyric acid receptor subunit alpha-6 |
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| Synonyms: | GABA A alpha6 | GABA receptor alpha-6 subunit | GABRA6 | GBRA6_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51029.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | GABA A alpha6 0 HUMAN::Q16445 |
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| Residue: | 453 |
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| Sequence: | MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKT
DIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRN
GKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYP
KSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKM
GYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYA
TAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEI
VLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQY
SRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE
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| BDBM50244263 |
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| n/a |
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| Name | BDBM50244263 |
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| Synonyms: | 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]quinazolin-3-yl 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]quinazoline-3-carboxylate | CHEMBL394710 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H20N6O6 |
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| Mol. Mass. | 560.5164 |
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| SMILES | Cn1c2c(ncn2c2ccc(cc2c1=O)C#C)C(=O)OCCOC(=O)c1ncn2c1n(C)c(=O)c1cc(ccc21)C#C |
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| Structure | 
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