| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM50378067 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_578238 (CHEMBL1051553) |
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| EC50 | 450±n/a nM |
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| Citation |  Maruyama, T; Seki, N; Onda, K; Suzuki, T; Kawazoe, S; Hayakawa, M; Matsui, T; Takasu, T; Ohta, M Discovery of novel thiourea derivatives as potent and selective beta3-adrenergic receptor agonists. Bioorg Med Chem17:5510-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-3 adrenergic receptor |
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| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43534.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 408 |
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| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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| BDBM50378067 |
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| n/a |
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| Name | BDBM50378067 |
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| Synonyms: | CHEMBL1203989 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26N4O4S |
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| Mol. Mass. | 466.553 |
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| SMILES | O[C@@H](CNCCc1ccc(NC(=S)Nc2cccc(c2)[N+]([O-])=O)cc1)COc1ccccc1 |r| |
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| Structure | 
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