| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
|---|
| Ligand | BDBM50378075 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_578238 (CHEMBL1051553) |
|---|
| EC50 | 810±n/a nM |
|---|
| Citation |  Maruyama, T; Seki, N; Onda, K; Suzuki, T; Kawazoe, S; Hayakawa, M; Matsui, T; Takasu, T; Ohta, M Discovery of novel thiourea derivatives as potent and selective beta3-adrenergic receptor agonists. Bioorg Med Chem17:5510-9 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-3 adrenergic receptor |
|---|
| Name: | Beta-3 adrenergic receptor |
|---|
| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 43534.88 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 408 |
|---|
| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
|
|
|
|---|
| BDBM50378075 |
|---|
| n/a |
|---|
| Name | BDBM50378075 |
|---|
| Synonyms: | CHEMBL1203996 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H29N3O3S |
|---|
| Mol. Mass. | 451.581 |
|---|
| SMILES | COc1cccc(NC(=S)Nc2ccc(CCNC[C@H](O)COc3ccccc3)cc2)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
