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TargetBeta-2 adrenergic receptor
LigandBDBM50378062
Substrate/Competitorn/a
Meas. Tech.ChEMBL_578239 (CHEMBL1051554)
EC50>100000±n/a nM
Citation Maruyama, TSeki, NOnda, KSuzuki, TKawazoe, SHayakawa, MMatsui, TTakasu, TOhta, M Discovery of novel thiourea derivatives as potent and selective beta3-adrenergic receptor agonists. Bioorg Med Chem17:5510-9 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor
Name:Beta-2 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50378062
n/a
NameBDBM50378062
Synonyms:CHEMBL1204005
TypeSmall organic molecule
Emp. Form.C25H27N5O2
Mol. Mass.429.5142
SMILESO[C@@H](CNCCc1ccc(cc1)N=C(NC#N)Nc1ccccc1)COc1ccccc1 |r,w:12.12|
Structure
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