| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Steryl-sulfatase |
|---|
| Ligand | BDBM50380213 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_811916 (CHEMBL2013286) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Lawrence Woo, LW; Leblond, B; Purohit, A; Potter, BV Synthesis and evaluation of analogues of estrone-3-O-sulfamate as potent steroid sulfatase inhibitors. Bioorg Med Chem20:2506-19 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Steryl-sulfatase |
|---|
| Name: | Steryl-sulfatase |
|---|
| Synonyms: | ARSC1 | ASC | Arylsulfatase C | STS | STS_HUMAN | Steroid sulfatase | Steryl-sulfate sulfohydrolase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 65503.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P08842 |
|---|
| Residue: | 583 |
|---|
| Sequence: | MPLRKMKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLAS
GGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAK
LLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTT
GFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPL
NCFMMRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFA
GKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGS
NGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRI
IDGRDLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNG
CFATHVCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQT
LPEVPDQFSWNNFLWKPWLQLCCPSTGLSCQCDREKQDKRLSR
|
|
|
|---|
| BDBM50380213 |
|---|
| n/a |
|---|
| Name | BDBM50380213 |
|---|
| Synonyms: | CHEMBL2011413 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H35NO4S |
|---|
| Mol. Mass. | 433.604 |
|---|
| SMILES | CCCc1cc2[C@H]3CC[C@@]4(C)[C@@H](CCC4=O)[C@@H]3CCc2c(CCC)c1OS(N)(=O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
