BindingDB PrimarySearch

Found 756 hits with Last Name = 'leblond' and Initial = 'b'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176918 ((2S)-aminobutyryl-(2S)-indoline carboxylic acid pr...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50121282 ((S)-1-((S)-2-aminobutanoyl)-N-butylindoline-2-carb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176940 ((2S)-aminobutyryl-(2S)-indoline carboxylic acid et...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176934 ((2S)-aminobutyryl-L-proline n-butylamide \| CHEMBL2...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176913 ((2S)-aminobutyryl-L-proline n-propylamide \| CHEMBL...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176939 ((2S)-1-((S)-2-aminobutanoyl)-4-benzyl-N-butylpyrro...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176936 ((2S)-aminobutyryl-L-proline n-pentylamide \| CHEMBL...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176927 ((2S)-aminobutyryl-L-proline 3-methylthiopropylamid...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176935 ((2S,4S)-1-((S)-2-aminobutanoyl)-N-butyl-4-fluoropy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176945 ((2S)-aminobutyryl-L-proline isobutylamide \| CHEMBL...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176922 ((2S)-aminobutyryl-(2S)-indoline carboxylic acid me...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176914 ((2S)-aminobutyryl-L-proline-(2S)-methylbutylamide ...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176920 ((S)-1-((S)-2-amino-3-methylbutanoyl)-N-butylpyrrol...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176932 ((2S)-aminobutyryl-L-prolinamide \| CHEMBL224063) Show SMILES CC[C@H](N)C(=O)N1CCC[C@H]1C(N)=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176928 (CHEMBL375490 \| L-valyl-L-proline hexylamide) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176926 (CHEMBL224628 \| L-norvalyl-L-prolinamide) Show SMILES CCC[C@H](N)C(=O)N1CCC[C@H]1C(N)=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176919 (CHEMBL388843 \| L-norleucyl-L-prolinamide) Show SMILES CCCC[C@H](N)C(=O)N1CCC[C@H]1C(N)=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176925 (CHEMBL224340 \| L-leucyl-L-prolinamide) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176943 ((S)-1-((S)-2-aminopropanoyl)pyrrolidine-2-carboxam...) Show SMILES C[C@H](N)C(=O)N1CCC[C@H]1C(N)=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176931 (CHEMBL376375 \| L-valyl-L-proline benzylamide) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176924 (CHEMBL224341 \| L-isoleucyl-L-prolinamide) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176930 ((2S)-aminobutyryl-L-proline (R)-sec-butylamide \| C...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176938 (CHEMBL388062 \| alpha-methylalanyl-L-proline butyla...) Show SMILES CCCCNC(=O)[C@@H]1CCCN1C(=O)C(C)(C)N \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176929 (CHEMBL375933 \| L-valyl-L-prolinamide) Show SMILES CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(N)=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176944 (1-((S)-2-aminobutanoyl)-N-butylazepane-2-carboxami...) Show SMILES CCCCNC(=O)C1CCCCCN1C(=O)[C@@H](N)CC \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176923 ((2S)-aminobutyryl-(R)-pipecolinic acid amide \| CHE...) Show SMILES CC[C@H](N)C(=O)N1CCCC[C@@H]1C(N)=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176921 ((2S)-aminobutyryl-(2S)-azetidine carboxamide \| CHE...) Show SMILES CC[C@H](N)C(=O)N1CC[C@H]1C(N)=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176915 ((2S)-aminobutyryl-L-proline (S)-sec-butylamide \| C...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176912 (CHEMBL225596 \| L-valyl-L-proline cyclohexylmethyla...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176911 ((2S)-aminobutyryl-L-pipecolinic acid n-butylamide ...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176916 ((2S)-aminobutyryl-(S)-nipecotamide \| CHEMBL223665) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176942 ((2S)-aminobutyryl-4-thia-L-prolinamide \| CHEMBL375...) Show SMILES CC[C@H](N)C(=O)N1CSC[C@@H]1C(N)=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176933 (CHEMBL390771 \| L-valyl-L-proline piperidinylamide) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176941 (CHEMBL224610 \| L-phenylalanyl-L-prolinamide) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176937 ((R)-1-((S)-2-amino-3-methylbutanoyl)-N-butylpyrrol...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50176917 (CHEMBL390838 \| L-valyl-L-proline-N-naphthylamide) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of TPPII in rat cererbral membrane				J Med Chem 48: 7333-42 (2005) Article DOI: 10.1021/jm0500830 BindingDB Entry DOI: 10.7270/Q2KK9CMS
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Steryl-sulfatase (Homo sapiens (Human))	BDBM50380208 (CHEMBL2011408) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0100	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometry				Bioorg Med Chem 20: 2506-19 (2012) Article DOI: 10.1016/j.bmc.2012.03.007 BindingDB Entry DOI: 10.7270/Q2XG9S4J
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Steryl-sulfatase (Homo sapiens (Human))	BDBM50380223 (CHEMBL2011422) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of steroid sulfatase in human placental microsomes using [3H]E1S as substrate after 30 mins by scintillation spectrometry				Bioorg Med Chem 20: 2506-19 (2012) Article DOI: 10.1016/j.bmc.2012.03.007 BindingDB Entry DOI: 10.7270/Q2XG9S4J
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Steryl-sulfatase (Homo sapiens (Human))	BDBM50380216 (CHEMBL364332) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of steroid sulfatase in human MCF7 cells using [3H]E1S as substrate after 20 hrs by scintillation spectrometry				Bioorg Med Chem 20: 2506-19 (2012) Article DOI: 10.1016/j.bmc.2012.03.007 BindingDB Entry DOI: 10.7270/Q2XG9S4J
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM125523 (US8772316, 6) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc.; Exonhit Therapeutics SA US Patent					Assay Description The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...				US Patent US8772316 (2014) BindingDB Entry DOI: 10.7270/Q2Q81BR8
Allergan, Inc.; Exonhit Therapeutics SA US Patent					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM187126 (US9670181, 6 4-(dibenzo[b,d]furan-2-ylmethyl)-1-et...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	7.4	25
ALLERGAN, INC.; EXONHIT THERAPEUTICS SA US Patent					Assay Description The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE� from Perkin Elmer). This c...				US Patent US9670181 (2017) BindingDB Entry DOI: 10.7270/Q21Z42KJ
ALLERGAN, INC.; EXONHIT THERAPEUTICS SA US Patent					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50434358 (CHEMBL2386770 \| US9446044, 68) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	7.5	25
DIAXONHIT US Patent					Assay Description The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...				US Patent US9446044 (2016) BindingDB Entry DOI: 10.7270/Q2610Z7J
DIAXONHIT US Patent					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM194437 (US9200016, 119 \| US9902710, Compound 119) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	7.4	37
Allergan, Inc.; Exonhit Therapeutics, SA US Patent					Assay Description The phosphodiesterase assay was developed using the LANCE cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1....				US Patent US9200016 (2015) BindingDB Entry DOI: 10.7270/Q2ZC81PH
Allergan, Inc.; Exonhit Therapeutics, SA US Patent					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM194437 (US9200016, 119 \| US9902710, Compound 119) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description The phosphodiesterase assay was developed using the LANCE� cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q2PC34QT
University of Mississippi					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50434353 (CHEMBL2386747 \| US9446044, 72) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	7.5	25
DIAXONHIT US Patent					Assay Description The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...				US Patent US9446044 (2016) BindingDB Entry DOI: 10.7270/Q2610Z7J
DIAXONHIT US Patent					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50434353 (CHEMBL2386747 \| US9446044, 72) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin)				Citation and Details BindingDB Entry DOI: 10.7270/Q2GH9NMG
TBA					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50434353 (CHEMBL2386747 \| US9446044, 72) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DYRK1A using [33P]-ATP incubated for 120 mins				Citation and Details BindingDB Entry DOI: 10.7270/Q2GH9NMG
TBA					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50434358 (CHEMBL2386770 \| US9446044, 68) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	7.5	25
DIAXONHIT US Patent					Assay Description The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...				US Patent US9446044 (2016) BindingDB Entry DOI: 10.7270/Q2610Z7J
DIAXONHIT US Patent					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50434353 (CHEMBL2386747 \| US9446044, 72) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin)				Citation and Details BindingDB Entry DOI: 10.7270/Q2GH9NMG
TBA					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM125567 (US8772316, 50) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc.; Exonhit Therapeutics SA US Patent					Assay Description The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...				US Patent US8772316 (2014) BindingDB Entry DOI: 10.7270/Q2Q81BR8
Allergan, Inc.; Exonhit Therapeutics SA US Patent					More data for this Ligand-Target Pair

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