| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 6 |
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| Ligand | BDBM50306710 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_839558 (CHEMBL2090365) |
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| EC50 | 13±n/a nM |
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| Citation |  Ginsburg-Shmuel, T; Haas, M; Grbic, D; Arguin, G; Nadel, Y; Gendron, FP; Reiser, G; Fischer, B UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety. Bioorg Med Chem20:5483-95 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 6 |
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| Name: | P2Y purinoceptor 6 |
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| Synonyms: | P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36452.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1511151 |
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| Residue: | 328 |
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| Sequence: | MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTR
TAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCI
SFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDL
SPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARM
AVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPIL
FYFTQKKFRRRPHELLQKLTAKWQRQGR
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| BDBM50306710 |
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| n/a |
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| Name | BDBM50306710 |
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| Synonyms: | ((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl trihydrogen diphosphate | CHEMBL1094759 | CHEMBL590494 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H13IN2O12P2 |
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| Mol. Mass. | 530.0577 |
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| SMILES | O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1cc(I)c(=O)[nH]c1=O |r| |
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| Structure | 
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