| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50425437 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_935745 (CHEMBL2321509) |
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| Ki | 9.0±n/a nM |
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| Citation |  Zajdel, P; Marciniec, K; Maslankiewicz, A; Grychowska, K; Satala, G; Duszynska, B; Lenda, T; Siwek, A; Nowak, G; Partyka, A; Wróbel, D; Jastrzebska-Wiesek, M; Bojarski, AJ; Wesolowska, A; Pawlowski, M Antidepressant and antipsychotic activity of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT1A/5-HT2A/5-HT7 and dopamine D2/D3 receptors. Eur J Med Chem60:42-50 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50425437 |
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| n/a |
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| Name | BDBM50425437 |
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| Synonyms: | CHEMBL2312935 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26Cl2N4O2S |
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| Mol. Mass. | 493.449 |
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| SMILES | Clc1cccc(N2CCN(CCCCNS(=O)(=O)c3cnc4ccccc4c3)CC2)c1Cl |
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| Structure | 
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