Compile Data Set for Download or QSAR

Found 550 hits with Last Name = 'duszynska' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM82517 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor in the rat brain (hippocampus) using [3H]-8-OH-DPAT				J Med Chem 39: 1125-9 (1996) Article DOI: 10.1021/jm950662c BindingDB Entry DOI: 10.7270/Q21Z43H2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM82517 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace the radioligand [3H]-OH-DPAT from binding to rat 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 14: 5863-6 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.09.029 BindingDB Entry DOI: 10.7270/Q22N51RZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from human dopamine D2L receptor expressed in HEK293 after 1 hr				Eur J Med Chem 60: 42-50 (2013) Article DOI: 10.1016/j.ejmech.2012.11.042 BindingDB Entry DOI: 10.7270/Q21V5G98
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50098551 ((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...) Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting				Bioorg Med Chem 19: 6750-9 (2011) Article DOI: 10.1016/j.bmc.2011.09.044 BindingDB Entry DOI: 10.7270/Q2028S0V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50098551 ((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...) Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Compound was evaluated in vitro for its ability to displace [3H]-8-hydroxy-2-(di-n-propylamino) tetralin binding from 5-hydroxytryptamine 1A receptor...				J Med Chem 35: 2369-74 (1992) BindingDB Entry DOI: 10.7270/Q2F18XP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50146087 (1,3-Dimethyl-8-[4-(4-phenyl-piperazin-1-yl)-butyl]...) Show SMILES Cn1c2nc3N(CCCCN4CCN(CC4)c4ccccc4)CCCn3c2c(=O)n(C)c1=O Show InChI InChI=1S/C24H33N7O2/c1-26-21-20(22(32)27(2)24(26)33)31-14-8-13-30(23(31)25-21)12-7-6-11-28-15-17-29(18-16-28)19-9-4-3-5-10-19/h3-5,9-10H,6-8,11-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Collegium Medicum of the Jagiellonian University Curated by ChEMBL					Assay Description Ability to bind to central serotonin 5-hydroxytryptamine 1A receptor in vitro in hippocampus of the rat brain using [3H]-8-OH-DPAT radioligand				J Med Chem 47: 2659-66 (2004) Article DOI: 10.1021/jm030946u BindingDB Entry DOI: 10.7270/Q2XG9QKJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50005135 (1-(3-Chloro-phenyl)-4-hexyl-piperazine | CHEMBL279...) Show SMILES CCCCCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C16H25ClN2/c1-2-3-4-5-9-18-10-12-19(13-11-18)16-8-6-7-15(17)14-16/h6-8,14H,2-5,9-13H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-8-hydroxy-2-(di-n-propylamino) tetralin binding from 5-hydroxytryptamine 1A receptor site in rat brain hippocampus				J Med Chem 35: 2369-74 (1992) BindingDB Entry DOI: 10.7270/Q2F18XP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50206353 (1-(adamantylcarbonyl)-N-{4-[4-(2-methoxyphenyl)pip...) Show SMILES COc1ccccc1N1CCN(CCCC[C@@H]2CCCN2C(=O)C23CC4CC(CC(C4)C2)C3)CC1 Show InChI InChI=1S/C30H45N3O2/c1-35-28-10-3-2-9-27(28)32-15-13-31(14-16-32)11-5-4-7-26-8-6-12-33(26)29(34)30-20-23-17-24(21-30)19-25(18-23)22-30/h2-3,9-10,23-26H,4-8,11-22H2,1H3/t23?,24?,25?,26-,30?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from serotonin 5HT1A receptor in rat brain hippocampus				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50186245 ((2S)-1-[(adamantan-1-yl)carbonyl]-N-{4-[4-(2-metho...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)[C@@H]2CCCN2C(=O)C23CC4CC(CC(C4)C2)C3)CC1 |r,TLB:24:26:29.28.33:31,THB:24:26:29:33.32.31,27:28:31:35.26.34,27:26:29.28.33:31,34:26:29:33.32.31,34:32:29:35.27.26| Show InChI InChI=1S/C31H46N4O3/c1-38-28-9-3-2-7-26(28)34-15-13-33(14-16-34)11-5-4-10-32-29(36)27-8-6-12-35(27)30(37)31-20-23-17-24(21-31)19-25(18-23)22-31/h2-3,7,9,23-25,27H,4-6,8,10-22H2,1H3,(H,32,36)/t23?,24?,25?,27-,31?/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane				Eur J Med Chem 44: 800-8 (2009) Article DOI: 10.1016/j.ejmech.2008.05.021 BindingDB Entry DOI: 10.7270/Q20Z7468
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50005127 (1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-8-hydroxy-2-(di-n-propylamino) tetralin binding from 5-hydroxytryptamine 1A receptor site in rat brain hippocampus				J Med Chem 35: 2369-74 (1992) BindingDB Entry DOI: 10.7270/Q2F18XP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50357975 (CHEMBL1917341) Show SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2cnc3ccccc3c2)CC1 Show InChI InChI=1S/C24H30N4O3S/c1-31-24-11-5-4-10-23(24)28-16-14-27(15-17-28)13-7-6-12-26-32(29,30)21-18-20-8-2-3-9-22(20)25-19-21/h2-5,8-11,18-19,26H,6-7,12-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation counting				Bioorg Med Chem 19: 6750-9 (2011) Article DOI: 10.1016/j.bmc.2011.09.044 BindingDB Entry DOI: 10.7270/Q2028S0V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50186236 (Adamantane-1-carboxylic acid ((S)-1-{4-[4-(2-metho...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(=O)C34CC5CC(CC(C5)C3)C4)C2=O)CC1 |r,TLB:22:24:27.26.31:29,THB:25:26:29:33.24.32,25:24:27.26.31:29,32:24:27:31.30.29,32:30:27:33.25.24| Show InChI InChI=1S/C30H42N4O4/c1-38-26-7-3-2-6-25(26)33-12-10-32(11-13-33)8-4-5-9-34-27(35)17-24(28(34)36)31-29(37)30-18-21-14-22(19-30)16-23(15-21)20-30/h2-3,6-7,21-24H,4-5,8-20H2,1H3,(H,31,37)/t21?,22?,23?,24-,30?/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane				Eur J Med Chem 44: 800-8 (2009) Article DOI: 10.1016/j.ejmech.2008.05.021 BindingDB Entry DOI: 10.7270/Q20Z7468
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50186236 (Adamantane-1-carboxylic acid ((S)-1-{4-[4-(2-metho...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(=O)C34CC5CC(CC(C5)C3)C4)C2=O)CC1 |r,TLB:22:24:27.26.31:29,THB:25:26:29:33.24.32,25:24:27.26.31:29,32:24:27:31.30.29,32:30:27:33.25.24| Show InChI InChI=1S/C30H42N4O4/c1-38-26-7-3-2-6-25(26)33-12-10-32(11-13-33)8-4-5-9-34-27(35)17-24(28(34)36)31-29(37)30-18-21-14-22(19-30)16-23(15-21)20-30/h2-3,6-7,21-24H,4-5,8-20H2,1H3,(H,31,37)/t21?,22?,23?,24-,30?/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from serotonin 5HT1A receptor in rat brain hippocampus				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50186254 (2-(bicyclo[2.2.1]heptan-2-yl)-N-((R)-1-(4-(4-(2-me...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C[C@@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1 Show InChI InChI=1S/C28H40N4O4/c1-36-25-7-3-2-6-24(25)31-14-12-30(13-15-31)10-4-5-11-32-27(34)19-23(28(32)35)29-26(33)18-22-17-20-8-9-21(22)16-20/h2-3,6-7,20-23H,4-5,8-19H2,1H3,(H,29,33)/t20?,21?,22?,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Affinity for 5HT1A receptor				Bioorg Med Chem Lett 16: 3406-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.035 BindingDB Entry DOI: 10.7270/Q2542N6V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50186254 (2-(bicyclo[2.2.1]heptan-2-yl)-N-((R)-1-(4-(4-(2-me...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C[C@@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1 Show InChI InChI=1S/C28H40N4O4/c1-36-25-7-3-2-6-24(25)31-14-12-30(13-15-31)10-4-5-11-32-27(34)19-23(28(32)35)29-26(33)18-22-17-20-8-9-21(22)16-20/h2-3,6-7,20-23H,4-5,8-19H2,1H3,(H,29,33)/t20?,21?,22?,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Affinity for 5HT1A receptor				Bioorg Med Chem Lett 16: 3406-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.035 BindingDB Entry DOI: 10.7270/Q2542N6V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50186245 ((2S)-1-[(adamantan-1-yl)carbonyl]-N-{4-[4-(2-metho...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)[C@@H]2CCCN2C(=O)C23CC4CC(CC(C4)C2)C3)CC1 |r,TLB:24:26:29.28.33:31,THB:24:26:29:33.32.31,27:28:31:35.26.34,27:26:29.28.33:31,34:26:29:33.32.31,34:32:29:35.27.26| Show InChI InChI=1S/C31H46N4O3/c1-38-28-9-3-2-7-26(28)34-15-13-33(14-16-34)11-5-4-10-32-29(36)27-8-6-12-35(27)30(37)31-20-23-17-24(21-31)19-25(18-23)22-31/h2-3,7,9,23-25,27H,4-6,8,10-22H2,1H3,(H,32,36)/t23?,24?,25?,27-,31?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Affinity for 5HT1A receptor				Bioorg Med Chem Lett 16: 3406-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.035 BindingDB Entry DOI: 10.7270/Q2542N6V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50206350 (CHEMBL390037 | N-((S)-1-{4-[4-(3-chlorophenyl)pipe...) Show SMILES Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1 |w:24.24,29.29,26.27,TEB:23:24:27.28:30| Show InChI InChI=1S/C27H37ClN4O3/c28-22-4-3-5-23(17-22)31-12-10-30(11-13-31)8-1-2-9-32-26(34)18-24(27(32)35)29-25(33)16-21-15-19-6-7-20(21)14-19/h3-5,17,19-21,24H,1-2,6-16,18H2,(H,29,33)/t19?,20?,21?,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from serotonin 5HT2A receptor in rat brain cortex				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50267043 (2-(2-(4-(3-chlorophenyl)piperazin-1-yl)ethyl)-2-az...) Show SMILES Clc1cccc(c1)N1CCN(CCN2C(=O)CC3(CCCCC3)C2=O)CC1 Show InChI InChI=1S/C21H28ClN3O2/c22-17-5-4-6-18(15-17)24-12-9-23(10-13-24)11-14-25-19(26)16-21(20(25)27)7-2-1-3-8-21/h4-6,15H,1-3,7-14,16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane				Eur J Med Chem 44: 800-8 (2009) Article DOI: 10.1016/j.ejmech.2008.05.021 BindingDB Entry DOI: 10.7270/Q20Z7468
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50261126 (CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCNS(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C24H29N3O3S/c1-30-24-10-5-4-9-23(24)27-17-15-26(16-18-27)14-6-13-25-31(28,29)22-12-11-20-7-2-3-8-21(20)19-22/h2-5,7-12,19,25H,6,13-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50017721 (1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...) Show SMILES [#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccccc2-[#6]=[#6]-c2ccccc-12 |c:16| Show InChI InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from 5-hydroxytryptamine 2A receptor of rat brain cortex				Bioorg Med Chem Lett 7: 1635-1638 (1997) Article DOI: 10.1016/S0960-894X(97)00291-6 BindingDB Entry DOI: 10.7270/Q2QZ29ZT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50155686 (2-{(E)-4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-but...) Show SMILES COc1ccccc1N1CCN(C\C=C\CN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H25N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-11H,12-17H2,1H3/b7-6+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace the radioligand [3H]-OH-DPAT from binding to rat 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 14: 5863-6 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.09.029 BindingDB Entry DOI: 10.7270/Q22N51RZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051165 (8-[4-(3,4-Dihydro-1H-isoquinolin-2-yl)-butyl]-8-az...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C22H30N2O2/c25-20-15-22(10-3-4-11-22)16-21(26)24(20)13-6-5-12-23-14-9-18-7-1-2-8-19(18)17-23/h1-2,7-8H,3-6,9-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor in the rat brain (hippocampus) using [3H]-8-OH-DPAT				J Med Chem 39: 1125-9 (1996) Article DOI: 10.1021/jm950662c BindingDB Entry DOI: 10.7270/Q21Z43H2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50005140 (1-(3-Chloro-phenyl)-4-pentyl-piperazine | CHEMBL27...) Show SMILES CCCCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C15H23ClN2/c1-2-3-4-8-17-9-11-18(12-10-17)15-7-5-6-14(16)13-15/h5-7,13H,2-4,8-12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-8-hydroxy-2-(di-n-propylamino) tetralin binding from 5-hydroxytryptamine 1A receptor site in rat brain hippocampus				J Med Chem 35: 2369-74 (1992) BindingDB Entry DOI: 10.7270/Q2F18XP5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HEK293 after 1 hr				Eur J Med Chem 60: 42-50 (2013) Article DOI: 10.1016/j.ejmech.2012.11.042 BindingDB Entry DOI: 10.7270/Q21V5G98
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50026916 (2-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-2-a...) Show SMILES COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCCC3)C2=O)CC1 Show InChI InChI=1S/C22H31N3O3/c1-28-19-8-4-3-7-18(19)24-14-11-23(12-15-24)13-16-25-20(26)17-22(21(25)27)9-5-2-6-10-22/h3-4,7-8H,2,5-6,9-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane				Eur J Med Chem 44: 800-8 (2009) Article DOI: 10.1016/j.ejmech.2008.05.021 BindingDB Entry DOI: 10.7270/Q20Z7468
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297895 (4-(2-methoxyphenyl)-N-(N-(naphthalen-1-ylmethyl)ca...) Show SMILES COc1ccccc1N1CCN(CC1)C(=O)NC(N)=NCc1cccc2ccccc12 |w:19.21| Show InChI InChI=1S/C24H27N5O2/c1-31-22-12-5-4-11-21(22)28-13-15-29(16-14-28)24(30)27-23(25)26-17-19-9-6-8-18-7-2-3-10-20(18)19/h2-12H,13-17H2,1H3,(H3,25,26,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.05	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in rat cortical membrane				Eur J Med Chem 44: 800-8 (2009) Article DOI: 10.1016/j.ejmech.2008.05.021 BindingDB Entry DOI: 10.7270/Q20Z7468
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051166 (1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CCC2=O)CC1 Show InChI InChI=1S/C19H27N3O3/c1-25-17-7-3-2-6-16(17)21-14-12-20(13-15-21)10-4-5-11-22-18(23)8-9-19(22)24/h2-3,6-7H,4-5,8-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor in the rat brain (hippocampus) using [3H]-8-OH-DPAT				J Med Chem 39: 1125-9 (1996) Article DOI: 10.1021/jm950662c BindingDB Entry DOI: 10.7270/Q21Z43H2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051166 (1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CCC2=O)CC1 Show InChI InChI=1S/C19H27N3O3/c1-25-17-7-3-2-6-16(17)21-14-12-20(13-15-21)10-4-5-11-22-18(23)8-9-19(22)24/h2-3,6-7H,4-5,8-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from serotonin 5HT1A receptor in rat brain hippocampus				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051166 (1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CCC2=O)CC1 Show InChI InChI=1S/C19H27N3O3/c1-25-17-7-3-2-6-16(17)21-14-12-20(13-15-21)10-4-5-11-22-18(23)8-9-19(22)24/h2-3,6-7H,4-5,8-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace the radioligand [3H]-OH-DPAT from binding to rat 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 14: 5863-6 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.09.029 BindingDB Entry DOI: 10.7270/Q22N51RZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50206351 ((S)-N-(1-(4-(4-(3-chlorophenyl)piperazin-1-yl)buty...) Show SMILES Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)C3CCCCC3)C2=O)CC1 |r| Show InChI InChI=1S/C25H35ClN4O3/c26-20-9-6-10-21(17-20)29-15-13-28(14-16-29)11-4-5-12-30-23(31)18-22(25(30)33)27-24(32)19-7-2-1-3-8-19/h6,9-10,17,19,22H,1-5,7-8,11-16,18H2,(H,27,32)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in rat cortical membrane				Eur J Med Chem 44: 800-8 (2009) Article DOI: 10.1016/j.ejmech.2008.05.021 BindingDB Entry DOI: 10.7270/Q20Z7468
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50206351 ((S)-N-(1-(4-(4-(3-chlorophenyl)piperazin-1-yl)buty...) Show SMILES Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)C3CCCCC3)C2=O)CC1 |r| Show InChI InChI=1S/C25H35ClN4O3/c26-20-9-6-10-21(17-20)29-15-13-28(14-16-29)11-4-5-12-30-23(31)18-22(25(30)33)27-24(32)19-7-2-1-3-8-19/h6,9-10,17,19,22H,1-5,7-8,11-16,18H2,(H,27,32)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from serotonin 5HT2A receptor in rat brain cortex				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50155690 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-cyclohe...) Show SMILES COc1ccccc1N1CCN(CC1)[C@H]1CC[C@@H](CC1)N1C(=O)c2ccccc2C1=O |wU:14.15,wD:17.22,(-7.13,3.8,;-6.38,2.44,;-7.18,1.11,;-8.72,1.11,;-9.49,-.22,;-8.73,-1.57,;-7.18,-1.57,;-6.41,-.24,;-4.87,-.22,;-4.08,-1.57,;-2.54,-1.57,;-1.77,-.24,;-2.54,1.11,;-4.08,1.11,;-.23,-.24,;.54,1.11,;2.08,1.09,;2.85,-.24,;2.06,-1.57,;.54,-1.57,;4.39,-.22,;5.32,-1.43,;4.86,-2.9,;6.77,-.94,;8.1,-1.66,;9.43,-.89,;9.41,.65,;8.06,1.39,;6.74,.6,;5.27,1.07,;4.77,2.54,)| Show InChI InChI=1S/C25H29N3O3/c1-31-23-9-5-4-8-22(23)27-16-14-26(15-17-27)18-10-12-19(13-11-18)28-24(29)20-6-2-3-7-21(20)25(28)30/h2-9,18-19H,10-17H2,1H3/t18-,19-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description In vitro ability to displace the radioligand [3H]-OH-DPAT from binding to rat 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 14: 5863-6 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.09.029 BindingDB Entry DOI: 10.7270/Q22N51RZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50357995 (CHEMBL202780) Show SMILES CC(C)(CCCN1CC[C@@H]2CCCC[C@H]2C1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H33NO2S/c1-21(2,25(23,24)20-11-4-3-5-12-20)14-8-15-22-16-13-18-9-6-7-10-19(18)17-22/h3-5,11-12,18-19H,6-10,13-17H2,1-2H3/t18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting				Bioorg Med Chem 19: 6750-9 (2011) Article DOI: 10.1016/j.bmc.2011.09.044 BindingDB Entry DOI: 10.7270/Q2028S0V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50289603 (2-(4-Methyl-piperazin-1-yl)-4,6-di-thiophen-2-yl-p...) Show SMILES CN1CCN(CC1)c1nc(cc(n1)-c1cccs1)-c1cccs1 Show InChI InChI=1S/C17H18N4S2/c1-20-6-8-21(9-7-20)17-18-13(15-4-2-10-22-15)12-14(19-17)16-5-3-11-23-16/h2-5,10-12H,6-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from 5-hydroxytryptamine 2A receptor of rat brain cortex				Bioorg Med Chem Lett 7: 1635-1638 (1997) Article DOI: 10.1016/S0960-894X(97)00291-6 BindingDB Entry DOI: 10.7270/Q2QZ29ZT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50289607 (4,6-Di-furan-3-yl-2-(4-methyl-piperazin-1-yl)-pyri...) Show SMILES CN1CCN(CC1)c1nc(cc(n1)-c1ccoc1)-c1ccoc1 Show InChI InChI=1S/C17H18N4O2/c1-20-4-6-21(7-5-20)17-18-15(13-2-8-22-11-13)10-16(19-17)14-3-9-23-12-14/h2-3,8-12H,4-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from 5-hydroxytryptamine 2A receptor of rat brain cortex				Bioorg Med Chem Lett 7: 1635-1638 (1997) Article DOI: 10.1016/S0960-894X(97)00291-6 BindingDB Entry DOI: 10.7270/Q2QZ29ZT
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50425434 (CHEMBL2312640) Show SMILES Clc1cccc(N2CCN(CCCCNS(=O)(=O)c3cncc4ccccc34)CC2)c1Cl Show InChI InChI=1S/C23H26Cl2N4O2S/c24-20-8-5-9-21(23(20)25)29-14-12-28(13-15-29)11-4-3-10-27-32(30,31)22-17-26-16-18-6-1-2-7-19(18)22/h1-2,5-9,16-17,27H,3-4,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from human dopamine D2L receptor expressed in HEK293 after 1 hr				Eur J Med Chem 60: 42-50 (2013) Article DOI: 10.1016/j.ejmech.2012.11.042 BindingDB Entry DOI: 10.7270/Q21V5G98
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297894 (2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...) Show SMILES O=S(=O)(c1ccccc1)C1(CCCN2CCc3ccccc3C2)CCC1 Show InChI InChI=1S/C22H27NO2S/c24-26(25,21-10-2-1-3-11-21)22(13-6-14-22)15-7-16-23-17-12-19-8-4-5-9-20(19)18-23/h1-5,8-11H,6-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50026917 (8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...) Show SMILES COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor in the rat brain (hippocampus) using [3H]-8-OH-DPAT				J Med Chem 39: 1125-9 (1996) Article DOI: 10.1021/jm950662c BindingDB Entry DOI: 10.7270/Q21Z43H2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50186243 (2-(bicyclo[2.2.1]heptan-2-yl)-N-((S)-1-(4-(4-(2-me...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1 |r,THB:24:25:28.29:31| Show InChI InChI=1S/C28H40N4O4/c1-36-25-7-3-2-6-24(25)31-14-12-30(13-15-31)10-4-5-11-32-27(34)19-23(28(32)35)29-26(33)18-22-17-20-8-9-21(22)16-20/h2-3,6-7,20-23H,4-5,8-19H2,1H3,(H,29,33)/t20?,21?,22?,23-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane				Eur J Med Chem 44: 800-8 (2009) Article DOI: 10.1016/j.ejmech.2008.05.021 BindingDB Entry DOI: 10.7270/Q20Z7468
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50425437 (CHEMBL2312935) Show SMILES Clc1cccc(N2CCN(CCCCNS(=O)(=O)c3cnc4ccccc4c3)CC2)c1Cl Show InChI InChI=1S/C23H26Cl2N4O2S/c24-20-7-5-9-22(23(20)25)29-14-12-28(13-15-29)11-4-3-10-27-32(30,31)19-16-18-6-1-2-8-21(18)26-17-19/h1-2,5-9,16-17,27H,3-4,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from human dopamine D2L receptor expressed in HEK293 after 1 hr				Eur J Med Chem 60: 42-50 (2013) Article DOI: 10.1016/j.ejmech.2012.11.042 BindingDB Entry DOI: 10.7270/Q21V5G98
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50289609 (4-Furan-3-yl-2-(4-methyl-piperazin-1-yl)-6-phenyl-...) Show SMILES CN1CCN(CC1)c1nc(cc(n1)-c1ccccc1)-c1ccoc1 Show InChI InChI=1S/C19H20N4O/c1-22-8-10-23(11-9-22)19-20-17(15-5-3-2-4-6-15)13-18(21-19)16-7-12-24-14-16/h2-7,12-14H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from 5-hydroxytryptamine 2A receptor of rat brain cortex				Bioorg Med Chem Lett 7: 1635-1638 (1997) Article DOI: 10.1016/S0960-894X(97)00291-6 BindingDB Entry DOI: 10.7270/Q2QZ29ZT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50186247 (CHEMBL210296 | N-[(3R)-1-{4-[4-(2-methoxyphenyl)pi...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C[C@@H](NC(=O)C34CC5CC(CC(C5)C3)C4)C2=O)CC1 |TLB:22:24:27:31.30.29,THB:25:26:29:33.24.32,25:24:27.26.31:29,32:24:27:31.30.29,32:30:27:33.25.24| Show InChI InChI=1S/C30H42N4O4/c1-38-26-7-3-2-6-25(26)33-12-10-32(11-13-33)8-4-5-9-34-27(35)17-24(28(34)36)31-29(37)30-18-21-14-22(19-30)16-23(15-21)20-30/h2-3,6-7,21-24H,4-5,8-20H2,1H3,(H,31,37)/t21?,22?,23?,24-,30?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Affinity for 5HT1A receptor				Bioorg Med Chem Lett 16: 3406-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.035 BindingDB Entry DOI: 10.7270/Q2542N6V
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50186243 (2-(bicyclo[2.2.1]heptan-2-yl)-N-((S)-1-(4-(4-(2-me...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1 |r,THB:24:25:28.29:31| Show InChI InChI=1S/C28H40N4O4/c1-36-25-7-3-2-6-24(25)31-14-12-30(13-15-31)10-4-5-11-32-27(34)19-23(28(32)35)29-26(33)18-22-17-20-8-9-21(22)16-20/h2-3,6-7,20-23H,4-5,8-19H2,1H3,(H,29,33)/t20?,21?,22?,23-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from serotonin 5HT1A receptor in rat brain hippocampus				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50357988 (CHEMBL1917354) Show SMILES CCN(CCCCN1CCN(CC1)c1ccccc1OC)S(=O)(=O)c1cnc2ccccc2c1 Show InChI InChI=1S/C26H34N4O3S/c1-3-30(34(31,32)23-20-22-10-4-5-11-24(22)27-21-23)15-9-8-14-28-16-18-29(19-17-28)25-12-6-7-13-26(25)33-2/h4-7,10-13,20-21H,3,8-9,14-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampus by liquid scintillation counting				Bioorg Med Chem 19: 6750-9 (2011) Article DOI: 10.1016/j.bmc.2011.09.044 BindingDB Entry DOI: 10.7270/Q2028S0V
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-methylspiperone from human dopamine D3 receptor expressed in HEK293 after 1 hr				Eur J Med Chem 60: 42-50 (2013) Article DOI: 10.1016/j.ejmech.2012.11.042 BindingDB Entry DOI: 10.7270/Q21V5G98
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50289602 (4-Furan-3-yl-2-(4-methyl-piperazin-1-yl)-6-thiophe...) Show SMILES CN1CCN(CC1)c1nc(cc(n1)-c1cccs1)-c1ccoc1 Show InChI InChI=1S/C17H18N4OS/c1-20-5-7-21(8-6-20)17-18-14(13-4-9-22-12-13)11-15(19-17)16-3-2-10-23-16/h2-4,9-12H,5-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from 5-hydroxytryptamine 2A receptor of rat brain cortex				Bioorg Med Chem Lett 7: 1635-1638 (1997) Article DOI: 10.1016/S0960-894X(97)00291-6 BindingDB Entry DOI: 10.7270/Q2QZ29ZT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50289608 (4-Furan-3-yl-2-(4-methyl-piperazin-1-yl)-pyrimidin...) Show SMILES CN1CCN(CC1)c1nccc(n1)-c1ccoc1 Show InChI InChI=1S/C13H16N4O/c1-16-5-7-17(8-6-16)13-14-4-2-12(15-13)11-3-9-18-10-11/h2-4,9-10H,5-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from 5-hydroxytryptamine 2A receptor of rat brain cortex				Bioorg Med Chem Lett 7: 1635-1638 (1997) Article DOI: 10.1016/S0960-894X(97)00291-6 BindingDB Entry DOI: 10.7270/Q2QZ29ZT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50146094 (8-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...) Show SMILES COc1ccccc1N1CCN(CCCn2c3nc4n(C)c(=O)n(C)c(=O)c4n3ccc2=O)CC1 Show InChI InChI=1S/C24H29N7O4/c1-26-21-20(22(33)27(2)24(26)34)31-12-9-19(32)30(23(31)25-21)11-6-10-28-13-15-29(16-14-28)17-7-4-5-8-18(17)35-3/h4-5,7-9,12H,6,10-11,13-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Collegium Medicum of the Jagiellonian University Curated by ChEMBL					Assay Description Ability to bind to central serotonin 5-hydroxytryptamine 1A receptor in vitro in hippocampus of the rat brain using [3H]-8-OH-DPAT radioligand				J Med Chem 47: 2659-66 (2004) Article DOI: 10.1021/jm030946u BindingDB Entry DOI: 10.7270/Q2XG9QKJ
					More data for this Ligand-Target Pair

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