| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50017688 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1364397 (CHEMBL3294266) |
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| IC50 | 1400±n/a nM |
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| Citation |  Li, BW; Zhang, FH; Serrao, E; Chen, H; Sanchez, TW; Yang, LM; Neamati, N; Zheng, YT; Wang, H; Long, YQ Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75. Bioorg Med Chem22:3146-58 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50017688 |
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| n/a |
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| Name | BDBM50017688 |
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| Synonyms: | CHEMBL3288960 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H15FO7 |
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| Mol. Mass. | 410.3487 |
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| SMILES | Oc1cc(O)c2c(c1)oc(c(O)c2=O)-c1ccc(OCc2ccc(F)cc2)c(O)c1 |
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| Structure | 
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