| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
|---|
| Ligand | BDBM50056415 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1366555 (CHEMBL3296578) |
|---|
| Ki | 19±n/a nM |
|---|
| Citation |  Castriconi, F; Paolino, M; Giuliani, G; Anzini, M; Campiani, G; Mennuni, L; Sabatini, C; Lanza, M; Caselli, G; De Rienzo, F; Menziani, MC; Sbraccia, M; Molinari, P; Costa, T; Cappelli, A Synthesis and structure-activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold. Eur J Med Chem82:36-46 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 4 |
|---|
| Name: | 5-hydroxytryptamine receptor 4 |
|---|
| Synonyms: | 5-HT4 | 5-hydroxytryptamine receptor 4 | 5HT4R_CAVPO | HTR4 | Serotonin 4 (5-HT4) receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 43735.29 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | 5-HT4 HTR4 GUINEA PIG::O70528 |
|---|
| Residue: | 388 |
|---|
| Sequence: | MDKLDANVSSKEGFGSVEKVVLLTFLSAVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWVYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHARQIQVLQRAGAPAEGRP
QPADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQLWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
TVECGGQWESQCHPAASSPLVAAQPIDT
|
|
|
|---|
| BDBM50056415 |
|---|
| n/a |
|---|
| Name | BDBM50056415 |
|---|
| Synonyms: | 2-piperidinopropyl 4-amino-5-chloro-2-methoxybenzoate | 4-Amino-5-chloro-2-methoxy-benzoic acid 3-piperidin-1-yl-propyl ester | CHEMBL83954 | RS 23597 | RS-23597-190 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H23ClN2O3 |
|---|
| Mol. Mass. | 326.818 |
|---|
| SMILES | COc1cc(N)c(Cl)cc1C(=O)OCCCN1CCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
