| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide FF receptor 2 |
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| Ligand | BDBM50029111 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1436234 (CHEMBL3387181) |
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| Ki | 75±n/a nM |
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| Citation |  Journigan, VB; Mésangeau, C; Vyas, N; Eans, SO; Cutler, SJ; McLaughlin, JP; Mollereau, C; McCurdy, CR Nonpeptide small molecule agonist and antagonist original leads for neuropeptide FF1 and FF2 receptors. J Med Chem57:8903-27 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide FF receptor 2 |
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| Name: | Neuropeptide FF receptor 2 |
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| Synonyms: | G-protein coupled receptor 74 | G-protein coupled receptor HLWAR77 | GPR74 | NPFF2 | NPFF2_HUMAN | NPFFR2 | NPGPR | Neuropeptide FF receptor 2 | Neuropeptide G-protein coupled receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60293.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPFF2 0 HUMAN::Q9Y5X5 |
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| Residue: | 522 |
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| Sequence: | MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRR
LGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWN
VNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHT
VTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVA
IAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQN
KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKN
QEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFA
HWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQ
LVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
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| BDBM50029111 |
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| n/a |
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| Name | BDBM50029111 |
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| Synonyms: | CHEMBL3360829 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H39N5O3 |
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| Mol. Mass. | 481.6303 |
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| SMILES | CC(=N)NCCC[C@H](NC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r,TLB:9:11:14:18.17.16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| |
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| Structure | 
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