| Reaction Details |
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 | Report a problem with these data |
| Target | cAMP-specific 3',5'-cyclic phosphodiesterase 4D |
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| Ligand | BDBM50044118 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1453489 (CHEMBL3362176) |
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| IC50 | 4700±n/a nM |
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| Citation |  Cheng, ZB; Deng, YL; Fan, CQ; Han, QH; Lin, SL; Tang, GH; Luo, HB; Yin, S Prostaglandin Derivatives: Nonaromatic Phosphodiesterase-4 Inhibitors from the Soft Coral Sarcophyton ehrenbergi. J Nat Prod77:1928-36 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| cAMP-specific 3',5'-cyclic phosphodiesterase 4D |
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| Name: | cAMP-specific 3',5'-cyclic phosphodiesterase 4D |
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| Synonyms: | 3',5'-cyclic phosphodiesterase | DPDE3 | PDE43 | PDE4D | PDE4D_HUMAN | Phosphodiesterase 4D |
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| Type: | Protein |
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| Mol. Mass.: | 91092.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q08499 |
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| Residue: | 809 |
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| Sequence: | MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPP
PPPSPQPQPQCPLQPPPPPPLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRA
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQA
NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPL
TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMC
DKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPL
DEQVEEEAVGEEEESQPEACVIDDRSPDT
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| BDBM50044118 |
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| n/a |
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| Name | BDBM50044118 |
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| Synonyms: | CHEMBL3331576 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H40O7 |
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| Mol. Mass. | 452.5809 |
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| SMILES | CCCCC[C@H](OC(C)=O)\C=C\[C@H]1[C@H](O)C[C@H](OC(C)=O)[C@@H]1C\C=C/CCCC(=O)OC |r| |
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| Structure | 
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