| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin-like domain-containing CTD phosphatase 1 |
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| Ligand | BDBM50087867 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1476058 (CHEMBL3428554) |
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| pH | 6±n/a |
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| IC50 | 4400±n/a nM |
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| Comments | extracted |
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| Citation |  He, Y; Guo, X; Yu, ZH; Wu, L; Gunawan, AM; Zhang, Y; Dixon, JE; Zhang, ZY A potent and selective inhibitor for the UBLCP1 proteasome phosphatase. Bioorg Med Chem23:2798-809 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ubiquitin-like domain-containing CTD phosphatase 1 |
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| Name: | Ubiquitin-like domain-containing CTD phosphatase 1 |
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| Synonyms: | Nuclear proteasome inhibitor UBLCP1 | UBCP1_HUMAN | UBLCP1 | Ubiquitin-like domain-containing CTD phosphatase 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 36803.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8WVY7 |
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| Residue: | 318 |
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| Sequence: | MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVK
LGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVEVENREENLLKISR
RVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIV
IWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFS
EFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAKLDDF
LDLNHKYWERYLSKKQGQ
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| BDBM50087867 |
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| n/a |
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| Name | BDBM50087867 |
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| Synonyms: | CHEMBL3426907 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H33NO5S |
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| Mol. Mass. | 483.62 |
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| SMILES | CCCCC(Oc1cc(O)c(cc1C#Cc1ccsc1)C(O)=O)C(=O)NC1CCCCCCC1 |
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| Structure | 
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