| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
|---|
| Ligand | BDBM50282510 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1621075 (CHEMBL3863358) |
|---|
| IC50 | 6770±n/a nM |
|---|
| Citation |  Wang, Z; Wu, J; Yang, X; Cai, P; Liu, Q; Wang, KDG; Kong, L; Wang, X Neuroprotective effects of benzyloxy substituted small molecule monoamine oxidase B inhibitors in Parkinson's disease. Bioorg Med Chem24:5929-5940 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] A |
|---|
| Name: | Amine oxidase [flavin-containing] A |
|---|
| Synonyms: | AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 59689.53 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21397 |
|---|
| Residue: | 527 |
|---|
| Sequence: | MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
|
|
|
|---|
| BDBM50282510 |
|---|
| n/a |
|---|
| Name | BDBM50282510 |
|---|
| Synonyms: | 7-(4-Chloro-benzyloxy)-3,4-dimethyl-chromen-2-one | 7-(4-chlorobenzyloxy)-3,4-dimethyl-2H-chromen-2-one | CHEMBL274030 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H15ClO3 |
|---|
| Mol. Mass. | 314.763 |
|---|
| SMILES | Cc1c(C)c(=O)oc2cc(OCc3ccc(Cl)cc3)ccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
