| Reaction Details |
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 | Report a problem with these data |
| Target | Sporulation kinase A |
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| Ligand | BDBM50218641 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_92581 (CHEMBL700426) |
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| IC50 | 380000±n/a nM |
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| Citation |  Weidner-Wells, MA; Ohemeng, KA; Nguyen, VN; Fraga-Spano, S; Macielag, MJ; Werblood, HM; Foleno, BD; Webb, GC; Barrett, JF; Hlasta, DJ Amidino benzimidazole inhibitors of bacterial two-component systems. Bioorg Med Chem Lett11:1545-8 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sporulation kinase A |
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| Name: | Sporulation kinase A |
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| Synonyms: | KINA_BACSU | Sporulation kinase A | Stage II sporulation protein F | Stage II sporulation protein J | gsiC | kinA | scoD | spoIIF | spoIIJ |
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| Type: | PROTEIN |
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| Mol. Mass.: | 69161.05 |
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| Organism: | Bacillus subtilis (strain 168) |
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| Description: | ChEMBL_105028 |
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| Residue: | 606 |
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| Sequence: | MEQDTQHVKPLQTKTDIHAVLASNGRIIYISANSKLHLGYLQGEMIGSFLKTFLHEEDQF
LVESYFYNEHHLMPCTFRFIKKDHTIVWVEAAVEIVTTRAERTEREIILKMKVLEEETGH
QSLNCEKHEIEPASPESTTYITDDYERLVENLPSPLCISVKGKIVYVNSAMLSMLGAKSK
DAIIGKSSYEFIEEEYHDIVKNRIIRMQKGMEVGMIEQTWKRLDGTPVHLEVKASPTVYK
NQQAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHNGKWVFMNESGISLFE
AATYEDLIGKNIYDQLHPCDHEDVKERIQNIAEQKTESEIVKQSWFTFQNRVIYTEMVCI
PTTFFGEAAVQVILRDISERKQTEELMLKSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQL
MKPTMEGNEHYFDIVFSELSRIELILSELLMLAKPQQNAVKEYLNLKKLIGEVSALLETQ
ANLNGIFIRTSYEKDSIYINGDQNQLKQVFINLIKNAVESMPDGGTVDIIITEDEHSVHV
TVKDEGEGIPEKVLNRIGEPFLTTKEKGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFK
ISFPKK
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| BDBM50218641 |
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| n/a |
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| Name | BDBM50218641 |
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| Synonyms: | CHEMBL39438 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28N2O3 |
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| Mol. Mass. | 380.48 |
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| SMILES | COC(=O)c1ccc2[nH]c(nc2c1)-c1cc(cc(c1O)C(C)(C)C)C(C)(C)C |
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| Structure | 
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