| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Proteasome subunit beta type-9 |
|---|
| Ligand | BDBM50232675 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1648454 (CHEMBL3997510) |
|---|
| IC50 | 51±n/a nM |
|---|
| Citation |  Johnson, HWB; Anderl, JL; Bradley, EK; Bui, J; Jones, J; Arastu-Kapur, S; Kelly, LM; Lowe, E; Moebius, DC; Muchamuel, T; Kirk, C; Wang, Z; McMinn, D Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit. ACS Med Chem Lett8:413-417 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Proteasome subunit beta type-9 |
|---|
| Name: | Proteasome subunit beta type-9 |
|---|
| Synonyms: | LMP2 | Low molecular mass protein 2 | Macropain chain 7 | Multicatalytic endopeptidase complex chain 7 | PSB9_HUMAN | PSMB6i | PSMB9 | Proteasome chain 7 | Proteasome subunit beta-1i | RING12 | Really interesting new gene 12 protein |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 23256.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_106197 |
|---|
| Residue: | 219 |
|---|
| Sequence: | MLRAGAPTGDLPRAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHER
IYCALSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMV
AGWDQREGGQVYGTLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIA
LAMSRDGSSGGVIYLVTITAAGVDHRVILGNELPKFYDE
|
|
|
|---|
| BDBM50232675 |
|---|
| n/a |
|---|
| Name | BDBM50232675 |
|---|
| Synonyms: | CHEMBL4100295 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H23N3O6 |
|---|
| Mol. Mass. | 413.4238 |
|---|
| SMILES | C[C@@]1(CO1)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)c1cccc(=O)[nH]1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
